In a nutshell This study compared the long-term safety and effectiveness of ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) and brentuximab vedotin (Adcedris; A) + AVD (doxorubicin, vinblastine, and dacarbazine) chemotherapy combinations in high-risk patients with advanced classical Hodgkin lymphoma (cHL). The data showed that the A+AVD...
Read MoreAdding S-1 to hormonal therapy in patients with ER+ HER2- breast cancer
In a nutshell This study investigated whether adding oral S-1 (Teysuno) to hormonal therapy improved outcomes in patients with estrogen receptor (ER)-positive and HER2-negative primary breast cancer (BC). The data showed that the combination of S-1 with hormonal therapy could be a potential treatment option for these patients. Some background...
Read MoreDoes anti-cancer therapy improve the outcomes of older patients with metastatic non-small cell lung cancer?
In a nutshell This article looked at whether anti-cancer treatments can improve the outcomes of older patients with metastatic (cancer that has spread to a new location) non-small cell lung cancer (mNSCLC). The authors found that outcomes were improved with anti-cancer therapies in these patients. Some background NSCLC is responsible...
Read MoreLong-term follow-up after bortezomib, thalidomide, and dexamethasone treatment followed by double stem cell transplant in patients with multiple myeloma.
In a nutshell This study compared long-term outcomes after treatment with bortezomib (Velcade), thalidomide (Thalomid), and dexamethasone (Ozurdex) or VTD compared to thalidomide and dexamethasone (TD) followed by double hematopoietic stem cell transplant (HSCT) in patients with newly diagnosed multiple myeloma (MM). The study found...
Read MoreLong term outcomes of nilotinib versus imatinib in chronic phase chronic myeloid leukemia
In a nutshell This study aimed to investigate the long-term outcomes of nilotinib (Tasigna) versus imatinib (Gleevec) in patients with chronic-phase chronic myeloid leukemia (CP-CML). This study concluded that nilotinib provided good long-term outcomes for these patients. Some background CML results from a gene...
Read MoreIs heart monitoring needed in patients with HER2-positive metastatic breast cancer using trastuzumab?
In a nutshell This article looked at the occurrence of heart-related side effects in patients with HER2-positive metastatic breast cancer (mBC) receiving trastuzumab (Herceptin). The authors found that non-smoking patients with a good heart function before receiving treatment have a low risk of heart toxicity (HT) after 4 years...
Read MoreDietary Supplement Warning, Again!
Lots of people take dietary supplements. Unfortunately, they are not all that their producers claim. A previous post notified readers of FDA warnings to dietary supplement producers. Today another dietary supplement warning has come out and it is especially pertinent as so many of us are experiencing sadness and depression due to social distancing and the...
Read MoreControlling brain metastasis with localized radiotherapy.
In a nutshell This study evaluated the impact of radiotherapy (RT) on controlling brain metastasis (BM). The study suggested that a single dose of RT was effective in controlling small BM. Larger BM could be controlled more effectively with multiple rounds of RT. Some background The spread of cancer from the original tumor to other parts of the...
Read MoreControlling brain metastasis with localized radiotherapy.
In a nutshell This study evaluated the impact of radiotherapy (RT) on controlling brain metastasis (BM). The study suggested that a single dose of RT was effective in controlling small BM. Larger BM could be controlled more effectively with multiple rounds of RT. Some background The spread of cancer from the original tumor to other parts of the body...
Read MoreControlling brain metastasis with localized radiotherapy.
In a nutshell This study evaluated the impact of radiotherapy (RT) on controlling brain metastasis (BM). The study suggested that a single dose of RT was effective in controlling small BM. Larger BM could be controlled more effectively with multiple rounds of RT. Some background The spread of cancer from the original tumor to other parts of the body...
Read MoreLooking for participants to test an experimental Keytruda-combination study treatment for Small Cell Neuroendocrine Prostate Cancer (SCNC)
In a nutshell This clinical trial is evaluating the safety and effectiveness of an experimental treatment, BXCL701, in combination with pembrolizumab (Keytruda) for people with small cell neuroendocrine prostate cancer (SCNPCa). The main outcome to be measured will be the response rate to the study treatment. The details Prostate cancer is the...
Read MoreEvaluating henagliflozin in patients with type 2 diabetes
In a nutshell This study tested the ability of henagliflozin (SHR3824) in controlling blood glucose levels in patients with type 2 diabetes (T2D). The authors found that henagliflozin alone was able to control glucose levels, reduce body weight and blood pressure in these patients. Some background Insulin is a hormone produced by the...
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