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Comparing the long-term effectiveness of integrated IMRT vs segmented 3D-CRT after modified breast removal surgery in breast cancer patients

Comparing the long-term effectiveness of integrated IMRT vs segmented 3D-CRT after modified breast removal surgery in breast cancer patients

Posted by on Apr 3, 2021 in Breast cancer | 0 comments

In a nutshell This study compared the long-term effectiveness of integrated intensity-modulated radiation therapy (IMRT) and segmented 3D-conventional radiotherapy (3D-CRT) following breast-removal surgery (radical mastectomy) in patients with breast cancer (BC). The data showed that integrated IMRT reduced the recurrence rate in the long-term with...

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Is nivolumab safe and effective for the treatment of advanced melanoma in the real-world clinical practice?

Is nivolumab safe and effective for the treatment of advanced melanoma in the real-world clinical practice?

Posted by on Apr 3, 2021 in Melanoma | 0 comments

In a nutshell This study evaluated the safety and effectiveness of nivolumab (Opdivo) in patients with advanced melanoma in a real-world practice. The study found that the safety and effectiveness of nivolumab in these patients were similar to that reported in clinical trials. Some background Melanoma is a form of skin cancer. In more advanced...

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Is olmutinib effective in treating T790M-positive unresponsive non-small cell lung cancer?

Is olmutinib effective in treating T790M-positive unresponsive non-small cell lung cancer?

Posted by on Apr 3, 2021 in Lung cancer | 0 comments

In a nutshell This article looked at the use of olmutinib (Olita) in the treatment of T790M-positive non-small cell lung cancer (NSCLC) that was previously unresponsive to a tyrosine kinase inhibitor (TKI). The authors concluded that olmutinib had clinical activity and manageable side effects in these patients. Some background NSCLC accounts for...

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Evaluating surgery and chemotherapy versus chemotherapy alone for the treatment of metastatic colorectal cancer.

Evaluating surgery and chemotherapy versus chemotherapy alone for the treatment of metastatic colorectal cancer.

Posted by on Mar 31, 2021 in Colorectal cancer | 0 comments

In a nutshell This study evaluated whether surgery of colorectal cancer (CRC) followed by chemotherapy (CT) improved the outcomes of patients with metastatic (spread) CRC compared to CT alone. The study found that there was no difference in patients' outcomes whether surgery was given or not. Some background CRC is the third most common cancer...

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Combining venetoclax and navitoclax with chemotherapy in patients with relapsed/refractory acute lymphoblastic leukemia and lymphoblastic lymphoma

Combining venetoclax and navitoclax with chemotherapy in patients with relapsed/refractory acute lymphoblastic leukemia and lymphoblastic lymphoma

Posted by on Mar 28, 2021 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the safety and effectiveness of venetoclax (Venclexta) and low-dose navitoclax (ABT-263) in combination with chemotherapy in patients with relapsed/refractory (r/r) acute lymphoblastic leukemia (ALL).  This study concluded that this treatment option was well tolerated and...

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Evaluating the effectiveness of BGD therapy in relapsed/refractory Hodgkin lymphoma

Evaluating the effectiveness of BGD therapy in relapsed/refractory Hodgkin lymphoma

Posted by on Mar 28, 2021 in Hodgkin's lymphoma | 0 comments

In a nutshell This study aimed to investigate the safety and effectiveness of the BGD (bendamustine, gemcitabine, and dexamethasone) regimen in patients with previously treated Hodgkin lymphoma (HL). This study concluded that BGD is well-tolerated and highly effective in these patients.  Some background Hodgkin lymphoma (HL) is a cancer that...

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Relapsed or refractory Hodgkin lymphoma: how does stopping and restarting nivolumab impact patient outcomes?

Relapsed or refractory Hodgkin lymphoma: how does stopping and restarting nivolumab impact patient outcomes?

Posted by on Mar 28, 2021 in Hodgkin's lymphoma | 0 comments

In a nutshell This study aimed to evaluate the safety and effectiveness of stopping and restarting nivolumab (Opdivo) in patients with relapsed or refractory (r/r) classical Hodgkin lymphoma (cHL).   The authors concluded that nivolumab retreatment is well tolerated and effective in patients who achieved complete response (CR; complete...

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Evaluating etanercept for IVF implantation

Evaluating etanercept for IVF implantation

Posted by on Mar 28, 2021 in Infertility | 0 comments

In a nutshell This study looked at etanercept (Enbrel) for women who have had repeated unsuccessful in vitro fertilization (IVF). It found that etanercept led to good pregnancy rates in these patients. Some background The uterus forms a connection between the vagina, which is open to the outside, and the inside of the body. If harmful bacteria...

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A reduction in salt intake improves the symptoms of overactive bladder

A reduction in salt intake improves the symptoms of overactive bladder

Posted by on Mar 28, 2021 in Overactive bladder | 0 comments

In a nutshell This study investigated the effects of salt intake reduction on overactive bladder (OAB) symptoms. Researchers suggested that the reduction in salt intake improved OAB symptoms. Some background OAB consists of urinary urgency with or without urge incontinence (leakage of urine). It is present in 16 to 19% of patients with urinary...

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CT-guided radioactive implant improves the outcomes of locally advanced rectal cancer

CT-guided radioactive implant improves the outcomes of locally advanced rectal cancer

Posted by on Mar 28, 2021 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of computed tomography (CT)-guided radioactive 125Iodine (RI) implantation in patients with recurrent locally advanced rectal cancer (LARC). Researchers suggested that CT-guided RI implantation is a good and safe treatment for patients with LARC that came back...

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