In a nutshell This study reported the effectiveness and safety outcomes of copanlisib (Aliqopa) and rituximab (Rituxan) combination for the treatment of patients with relapsed indolent (painless) non-Hodgkin lymphoma (NHL). The data showed that this combination improved the outcomes of these patients with manageable side effects. Some background...
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In a nutshell This study investigated the effectiveness and safety of different regimens containing pegylated liposomal doxorubicin (PLD; Doxil) for patients with newly diagnosed multiple myeloma (NDMM). The data showed that the different PLD treatment regimens had promising effectiveness with manageable side effects. Some background Multiple...
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In a nutshell This study investigated the effectiveness and safety outcomes of radiotherapy given at the same time (concurrent chemoradiotherapy; cCRT) or after chemotherapy (sequential chemoradiotherapy; sCRT) for the treatment of patients with advanced non-small-cell lung cancer (NSCLC). The data showed that cCRT improved the long-term...
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In a nutshell The study compared patient-reported outcomes (PRO) in patients receiving continuous androgen deprivation therapy (CADT) vs intermittent androgen deprivation therapy (IADT) for locally advanced prostate cancer (PCa). The study reported that PROs were significantly improved with IADT. Some background ADT is a hormonal therapy...
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In a nutshell This study aimed to investigate the long-term outcomes for children with acute myeloid leukemia (AML) who were treated with low-dose chemotherapy (LDC). This study concluded that there is a high remission rate for these patients and that long-term survival is similar to patients who...
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In a nutshell This study compared the safety and durability of one injection of OnabotulinumtoxinA (Botox; OBT-A) in the bladder trigone vs 20 injections avoiding this region for the treatment of overactive bladder (OAB). Researchers suggested that one OBT-A trigone injection is a safe and durable treatment option for these patients. Some...
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In a nutshell The aim of this study was to evaluate if hepatic arterial infusion chemotherapy (HAIC) could be beneficial for patients with colorectal cancer (CRC) that has spread to the liver (liver metastasis; LM). The study found that HAIC improved the outcome of these patients. Some background CRC is one of the most common types of cancer...
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In a nutshell This study evaluated the impact of non-drug therapy on the quality of life (QoL) of patients with colorectal cancer (CRC). The study found that non-drug therapies such as psychological, social, and physical activities were associated with reduced anxiety, depression, and improved QoL. Some background CRC is one of the most...
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In a nutshell The aim of this study was to evaluate the addition of isatuximab (Sarclisa) to pomalidomide (Pomalyst) and dexamethasone (Decadron) therapy for patients with relapsed/refractory (r/r) multiple myeloma (MM). The study found that patients who were given isatuximab had a better outcome. Some background MM is a type of blood cancer...
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In a nutshell This study investigated the effectiveness and safety of re-irradiation in the treatment of patients with relapsed prostate cancer (PCa). The data showed that the use of re-irradiation in these patients was associated with good outcomes and low toxicity. Some background Radiotherapy (RT) is an effective treatment for localized prostate...
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In a nutshell This study investigated whether immune-related side effects (irSEs) could predict the effectiveness of immune checkpoint inhibitors (ICIs) in patients with lung cancer. The data showed that the occurrence of skin, hormone, and gastrointestinal irSEs could predict the effectiveness of immunotherapy in these patients. Some background...
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In a nutshell This article compared the outcomes of older patients with low-risk breast cancer treated with accelerated partial breast irradiation (APBI) or ultra-APBI. The authors found that both treatment methods resulted in similar outcomes and side effects in these patients. Some background Breast cancer is the most commonly diagnosed...
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