In a nutshell This study investigated the use of water vapor thermal therapy using the Rezum system as a minimally invasive treatment option for benign prostatic hyperplasia (BPH). The authors concluded that Rezum is a good minimally invasive treatment option that showed promising results for patients with BPH. Some background BPH is a...
Read MoreEvaluating long-term effectiveness and safety of venetoclax patients with for non-Hodgkin lymphoma
In a nutshell This early study looked at the long-term results of the targeted treatment venetoclax (Venclexta) for patients with relapsed non-Hodgkin lymphoma (NHL). It found that venetoclax is a safe and effective treatment and that some patients have a durable response. Some background NHL is a group of cancers of a type of white blood...
Read MoreComparing the safety and effectiveness of pyrotinib versus trastuzumab etamsine for the treatment of HER2-positive metastatic breast cancer.
In a nutshell This study compared the safety and effectiveness between pyrotinib (SHR-1258) and trastuzumab emtansine (T-DM1; Kadcyla) in patients with HER2+ metastatic breast cancer (BC) after previous treatment with trastuzumab (Herceptin) and chemotherapy. The data showed that pyrotinib may be more effective than T-DM1 for these patients. Some...
Read MoreEvaluating the effectiveness and safety of chemotherapy before surgery for locally advanced colon cancer.
In a nutshell This study investigated the safety, effectiveness, and side effect profile of chemotherapy given before surgery for the treatment of patients with locally advanced colon cancer (LACC). The data showed that this treatment was safe and effective with manageable side effects for these patients. Some background Colorectal cancer (CRC) is one...
Read MoreRestoreX improves erectile function outcomes after prostate surgery
In a nutshell This study investigated the effectiveness of RestoreX penile traction device in the treatment of penile complications after prostate surgery. Researchers suggested that RestoreX improves penis length and sexual function after prostate surgery. Some background Prostate surgery can impact male sexual function. The effects can go from...
Read MoreComparing water vapor thermal therapy and prostatic urethral lift in the treatment of benign prostatic hyperplasia
In a nutshell This study compared water vapor thermal therapy using the Rezum system and prostatic urethral lift (PUL) in the treatment of men with urinary symptoms from benign prostatic hyperplasia (BPH). Researchers suggested that both treatments improve symptoms and the quality of life of these patients. Some background Benign prostatic...
Read MoreEvaluating the effectiveness of salvage radiotherapy for recurrence after prostate surgery in patients with localized prostate cancer.
In a nutshell This study evaluated the effectiveness of salvage radiotherapy (RT) in patients with recurrence of prostate cancer (PCa) after prostate surgery. The study found that salvage RT was effective in the management of PCa recurrence with manageable side effects. Some background Localized prostate cancer (PCa) is a form of cancer that...
Read MoreDoes focal laser ablation improve outcomes in the long-term for patients with prostate cancer?
In a nutshell The study aimed to understand the long-term outcomes of focal laser therapy (FLT) in patients with prostate cancer. The study showed that this treatment has long-term survival without recurrence in certain patients. Some background Surgical removal of the prostate gland is often recommended as a treatment for...
Read MoreLevodopa/carbidopa intestinal gel improves off symptoms in the long-term in patients with advanced Parkinson´s disease
In a nutshell This study reviewed the long-term effects of levodopa/carbidopa intestinal gel (LCIG; Duodopa®) in patients with Parkinson´s disease (PD) and wearing-off symptoms. This study concluded that LCIG reduced off-time and improved off-symptoms in the long-term in these patients. Some background PD is a chronic disorder that...
Read MoreComparing pembrolizumab and brentuximab vedotin for the treatment of patients with relapsed or refractory classical Hodgkin lymphoma.
In a nutshell The authors compared the safety and effectiveness of pembrolizumab (Keytruda) and brentuximab vedotin (BV; Adcetris) for the treatment of patients with relapsed or refractory (r/r) classical Hodgkin lymphoma (cHL). The study found that pembrolizumab had better survival without cancer worsening compared to BV in these...
Read MoreInotuzumab ozogamicin with bosutinib for relapsed/refractory Philadelphia chromosome-positive ALL or lymphoid blast phase of CML
In a nutshell This study aimed to investigate if a combination of inotuzumab ozogamicin (InO; Besponsa) and bosutinib (Bo; Bosulif) was safe and effective in patients with relapsed/refractory (r/r) Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia (ALL) or lymphoid blast phase (BP) chronic myeloid leukemia...
Read MoreEvaluating the long-term outcomes of apalutamide plus androgen deprivation therapy in metastatic castration-sensitive prostate cancer
In a nutshell This study reported the long-term effectiveness and safety outcomes of apalutamide (Erleada) in combination with androgen deprivation therapy (ADT) for the treatment of metastatic castration-sensitive prostate cancer (mCSPC). The data showed that this combination improved survival, delayed castration resistance, and maintained the...
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