In a nutshell This study evaluated the effects of bosutinib (Bosulif) on the heart in patients with chronic myeloid leukemia (CML). This study concluded that bosutinib was associated with heart-related side effects, particularly in high-risk patients. Some background Previous studies have shown that bosutinib is effective and well-tolerated. However,...
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In a nutshell This study evaluated the side effects associated with anthracycline treatment in patients with acute myeloid leukemia (AML) who undergo stem cell transplantation (SCT). This study concluded that anthracycline treatment may impact survival outcomes for these patients after a SCT. Some background Cytarabine (Ara-C) plus an anthracycline...
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In a nutshell This study investigated the impact of adverse events (AEs) of treatment with vemurafenib (Zelboraf) and cobimetinib (Cotellic) on survival in patients with melanoma. They found that early side effects requiring dose reduction had a positive effect on treatment outcomes. Some background Some melanoma tumors are caused by...
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In a nutshell This study aimed to investigate the risk of cardiovascular (heart and blood vessel) side effects in patients with chronic myeloid leukemia who were treated with tyrosine kinase inhibitors. This study concluded that these side effects were more frequent in this group of patients. Some background Cardiovascular events (CVE) have been...
Read MoreIn a nutshell This study looked at the management of side effects of bosutinib (Bosulif) in the treatment of chronic myeloid leukemia. Researchers found that bosutinib was safe in the treatment of patients in whom other medications have failed. Some background Chronic myeloid leukemia is a cancer of the bone marrow. It can lead to an abnormal...
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In a nutshell This study looked at the use of obinutuzumab (Gazyva) pretreatment to reduce side effects of chemotherapy in patients with chronic lymphocytic leukemia (CLL). Researchers found that obinutuzumab pretreatment is effective in reducing chemotherapy side effects in these patients. Some background Treatment of CLL involves...
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In a nutshell This study wanted to find out if patients with melanoma who had immune system side effects after treatment with nivolumab (Opdivo) had better outcomes than patients without side effects. The study found that the patients who had side effects from using nivolumab ended up with better responses to treatment and...
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In a nutshell This study wanted to find out if patients with melanoma who had immune system side effects after treatment with nivolumab (Opdivo) had better outcomes than patients without side effects. The study found that the patients who had side effects from using nivolumab ended up with better responses to treatment and...
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In a nutshell This study wanted to find out if using a cream containing atorvastatin (Lipitor) on the skin of women who had radiation treatment for breast cancer would help with some of the negative side effects. The study found that using atorvastatin reduced itching, swelling and pain in patients receiving radiation therapy for breast cancer. Some...
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In a nutshell This study evaluated the side effects and impact of medical cannabis on the symptoms of Parkinson’s disease (PD). This study concluded that medical cannabis improved PD symptoms and did not cause major side effects. Some background PD is a progressive disease caused by loss of brain cells that make dopamine. Dopamine is a chemical...
Read MoreIn a nutshell This study reviewed previous research to assess the effects of drugs called antimuscarinics to treat patients with overactive bladder. Results from 16 studies concluded that antimuscarinics were linked to more side effects. Some background Overactive bladder is a condition that can lower quality of life by increasing...
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In a nutshell This study investigated respiratory side effects in patients with non-Hodgkin’s lymphoma (NHL) who received chemotherapy containing rituximab (Rituxan). This study concluded that these side effects are common and associated with increased mortality in these patients. Some background Non-Hodgkin’s lymphoma patients treated...
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