In a nutshell This study evaluated whether patients with non-small-cell lung cancer (NSCLC) having genetic mutations could benefit from epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) therapy after surgery. The data showed that EGFR-TKI therapy after surgery significantly improved survival without disease progression in...
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In a nutshell This study looked at the use of osimertinib (Tagrisso) for the treatment of EGFR-mutant advanced non-small-cell lung cancer (NSCLC) in a real-world practice. It found that osimertinib was confirmed to improve survival without cancer progressing, while the occurrence of blood clots was more common in a real-world...
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In a nutshell This study examined the association of physical activity (PA) and sedentary time (ST) with pain, fatigue, and depressive symptoms over time among survivors of breast cancer (BC). The data showed that lower ST and higher PA is associated with lower depressive symptoms in long-term survivors of BC. Some background BC is one of the most...
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In a nutshell This study evaluated the occurrence and clinical predictors of peripheral neuropathy (PN; nerve damage) in long-term survivors of breast cancer (BC). The data showed that PN is an important long-term consequence of taxane-based chemotherapy in survivors of BC. Some background BC is one of the most common forms of cancer in women....
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In a nutshell This study determined the percentage of men with benign prostatic hyperplasia (BPH) that still needed BPH medication after surgical therapy for lower urinary tract symptoms (LUTS). The authors concluded that laser enucleation of the prostate (LEP) had the lowest percentage of patients that still needed BPH medication. Some...
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In a nutshell This study reviewed the initial management of benign prostatic hyperplasia (BPH). Some background BPH is a condition in which the prostate grows and can compress the urethra (the tube that passes urine out of the bladder), leading to difficulty passing urine. Symptoms include needing to urinate frequently,...
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In a nutshell This study looked at the use of sacral neuromodulation (SNM) with the InterStim device in patients with overactive bladder (OAB). It found that SNM improved the symptoms of OAB over 3 years. Some background OAB is a condition in which the bladder contracts involuntarily leading to a sudden, urgent need to urinate....
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In a nutshell This study investigated how people with myeloma responded to vaccines against COVID-19. It found that roughly half of the patients with multiple myeloma (MM) and most patients with other types of myeloma had protection against serious illness after the vaccine. The response to the vaccine was weaker for patients using certain treatments,...
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In a nutshell This study described the real-world effectiveness and safety of arsenic trioxide (ATO; Trisenox) combined with all-trans retinoic acid (ATRA; Vesanoid), without chemotherapy, in patients with newly diagnosed acute promyelocytic leukemia (APL). The authors concluded that a combination of ATO and ATRA showed good results for the...
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In a nutshell This study looked at the use of two types of stem cell transplant (SCT) in the treatment of T-cell lymphoma. It found that both haploidentical and umbilical cord blood SCT were good options for these patients. Some background T-cell lymphoma is a cancer affecting a certain type of blood cell called T-cells. T-cells are...
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In a nutshell This study aimed to investigate the safety and effectiveness of venetoclax (Venclexta) combined with intensive chemotherapy in patients aged 65 or younger with acute myeloid leukemia (AML). This study concluded that venetoclax added to intensive chemotherapy was safe and effective in these...
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In a nutshell This study evaluated the best approach for treating lateral lymph node (LLNs) metastasis in patients with locally advanced rectal cancer (LARC). The data showed that a radiation dose boost is an effective way of increasing the response rate and decreasing recurrence rates in these patients. Some background Rectal cancer (RC) is one...
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