In a nutshell This study evaluated the antibody response and side effects associated with COVID-19 vaccines administration in patients with type 1 (T1D) and type 2 diabetes (T2D), people without diabetes. The data showed similar immune responses in patients with and without diabetes after the second COVID-19 vaccine,...
Read MoreCan high-frequency spinal cord stimulation provide relief to patients with painful diabetic nerve disease?
In a nutshell This study evaluated the long-term impact of 10-kHz spinal cord stimulation (SCS) in patients with painful diabetic neuropathy (PDN; nerve disease) and refractory symptoms. The data supported the use of 10-kHz SCS for important, durable pain relief over 12 months in these patients. Some background Diabetic sensorimotor peripheral...
Read MoreInvestigating the effectiveness and safety of combining low-intensity extracorporeal shock wave therapy with tadalafil and L-arginine for the treatment of erectile dysfunction.
In a nutshell This study investigated the effectiveness and safety of combining low-intensity extracorporeal shock wave therapy (Li-ESWT) with tadalafil (Cialis) and L-arginine for the treatment of patients with mild and moderate erectile dysfunction (ED). The data showed that daily therapy with tadalafil and L-arginine increased the...
Read MoreEvaluating the risk factors associated with radiation skin irritation after radiotherapy in patients with breast cancer
In a nutshell This study evaluated the risk factors associated with acute radiation dermatitis (ARD; skin irritation) after radiotherapy (RT) in patients with breast cancer (BC). The data showed that patients with diabetes, smokers, and those with a body mass index (BMI; a measure of body weight in relation to height) of more than 25 kg/m2 had a...
Read MoreEvaluating quality of life in patients with relapsed or refractory multiple myeloma treated with idecabtagene vicleucel
In a nutshell This study aimed to investigate the effect of idecabtagene vicleucel (ABECMA; ide-cel) treatment on health-related quality of life (HR-QoL) in patients with relapsed or refractory (r/r) multiple myeloma (MM). This study concluded that this treatment improves HR-QoL for these patients. Some...
Read MoreEvaluating the effectiveness and safety of vagus nerve stimulation for improving arm function after ischemic stroke.
In a nutshell This study evaluated the effectiveness and safety of vagus nerve stimulation (VNS) for improving upper limb function in patients after ischemic stroke. The data showed that VNS was safe and improved upper limb function in these patients. Some background An ischemic stroke happens when blood flow through the blood vessels that supply...
Read MoreEvaluating the effectiveness and safety of ropinirole for the treatment of Parkinson’s disease.
In a nutshell This study evaluated the effectiveness and safety of ropinirole (Requip) for the treatment of patients with Parkinson’s disease (PD). The data showed that ropinirole was effective in improving motor function and daily living of patients with PD but was associated with an increase in side effects. Some background Parkinson's...
Read MoreComparing the effectiveness and safety of TAS-102 with or without bevacizumab in patients with metastatic colorectal cancer.
In a nutshell This study evaluated the effectiveness and safety of bevacizumab (Avastin) plus TAS-102 (Lonsurf; trifluridine-tipiracil) versus TAS-102 alone for the treatment of patients with metastatic colorectal cancer (mCRC). The data showed that bevacizumab combined with TAS-102 was effective with manageable side effects in improving the outcomes...
Read MoreWhich sequence of treatment should be given first – local or systemic treatment for patients with non-small cell lung cancer and brain metastases?
In a nutshell This study evaluated which sequence of treatment should be given first, local or systemic (whole-body) treatment for patients with non-small cell lung cancer (NSCLC) and brain metastases (BMs). The data showed that systemic treatment followed by local treatment was associated with longer survival for patients with NSCLC and BM. Some...
Read MoreComparing chiglitazar and sitagliptin effectiveness on glucose variations, insulin resistance and inflammation levels in patients with type 2 diabetes.
In a nutshell This study compared the effectiveness of chiglitazar (Bilessglu) and sitagliptin (Januvia) on glycemic (blood glucose) variations, insulin resistance, and inflammation levels in patients with type 2 diabetes (T2D). The data showed that chiglitazar treatment was more effective at improving insulin resistance and inflammation compared...
Read MoreIs chemotherapy after surgery followed by atezolizumab a good treatment option in patients with early stage non-small-cell lung cancer?
In a nutshell The study aimed to investigate the effectiveness and safety of atezolizumab (Tecentriq) versus best supportive care after chemotherapy in patients with resected early-stage non-small-cell lung cancer (NSCLC). The study showed atezolizumab is effective and has better outcomes than best supportive in these...
Read MoreEvaluating therapies after CAR-T Cell treatment in patients with relapsed and refractory ALL
In a nutshell The study aimed to investigate if allogeneic hematopoietic stem cell transplant (alloHSCT) was a suitable treatment strategy for patients with relapsed/refractory (r/r) acute lymphoblastic leukemia (ALL) after chimeric antigen receptor (CAR) T-cell therapy. This study concluded that this was a suitable treatment...
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