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Evaluating the long-term effectiveness and safety of injections under the skin of daratumumab versus intravenous infusions for patients with relapsed or refractory multiple myeloma.

Evaluating the long-term effectiveness and safety of injections under the skin of daratumumab versus intravenous infusions for patients with relapsed or refractory multiple myeloma.

Posted by on Sep 20, 2022 in Multiple Myeloma | 0 comments

In a nutshell This study reported the final effectiveness and safety of subcutaneous (SC) injections versus intravenous (IV) infusions of daratumumab (Darzalex) in patients with relapsed or refractory multiple myeloma (MM). The data showed that daratumumab SC injections were as effective and caused fewer side effects than IV infusions over the long term...

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Evaluating the effectiveness and safety of continuous subcutaneous night-time only apomorphine for the treatment of insomnia in patients with Parkinson’s disease.

Evaluating the effectiveness and safety of continuous subcutaneous night-time only apomorphine for the treatment of insomnia in patients with Parkinson’s disease.

Posted by on Sep 18, 2022 in Parkinson's Disease | 0 comments

In a nutshell This study evaluated the effectiveness and safety of continuous subcutaneous night-time only apomorphine (Apokyn) infusion for the treatment of insomnia in patients with Parkinson’s disease (PD). The data showed that continuous subcutaneous night-time only apomorphine was effective in improving sleep disturbances in patients with...

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Evaluating the long-term effectiveness and safety of palbociclib plus fulvestrant treatment in patients with HR+/HER2- advanced BC.

Evaluating the long-term effectiveness and safety of palbociclib plus fulvestrant treatment in patients with HR+/HER2- advanced BC.

Posted by on Sep 18, 2022 in Breast cancer | 0 comments

In a nutshell This study evaluated the long-term effectiveness and safety of palbociclib (Ibrance) plus fulvestrant (Faslodex) in patients with hormone receptor-positive (HR+) and HER2-negative (HER2-) advanced breast cancer (BC). The data showed that adding palbociclib to fulvestrant was safe and significantly improved the overall survival over the...

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Evaluating the effectiveness and safety of venetoclax with dose-adjusted EPOCH-R as initial therapy for patients with aggressive B-cell lymphoma.

Evaluating the effectiveness and safety of venetoclax with dose-adjusted EPOCH-R as initial therapy for patients with aggressive B-cell lymphoma.

Posted by on Sep 18, 2022 in Non-Hodgkin lymphoma | 0 comments

In a nutshell This study evaluated the effectiveness and safety of adding venetoclax (Venclexta) to a dose-adjusted EPOCH-R (etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab) regimen as initial therapy in patients with aggressive B-cell lymphoma. The data showed that venetoclax with dose-adjusted EPOCH-R was effective...

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Evaluating the short-term functional outcomes and safety of holmium and thulium fiber laser enucleation of the prostate treatment for patients with benign prostatic hyperplasia.

Evaluating the short-term functional outcomes and safety of holmium and thulium fiber laser enucleation of the prostate treatment for patients with benign prostatic hyperplasia.

Posted by on Sep 18, 2022 in Benign prostatic hyperplasia | 0 comments

In a nutshell This study evaluated the short-term functional outcomes and safety of holmium (HoLEP) and thulium fiber laser enucleation of the prostate (ThuFLEP) treatment for patients with benign prostatic hyperplasia (BPH). The data showed that both HoLEP and ThuFLEP surgeries are similar in terms of functional outcomes and safety in these patients....

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Evaluating ponatinib treatment in any phase of treatment in patients with chronic myeloid leukemia resistant or intolerant to other tyrosine kinase inhibitors

Evaluating ponatinib treatment in any phase of treatment in patients with chronic myeloid leukemia resistant or intolerant to other tyrosine kinase inhibitors

Posted by on Sep 18, 2022 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the safety and effectiveness of ponatinib (Iclusig) in patients with chronic myeloid leukemia (CML) who were resistant or intolerant to previous tyrosine kinase inhibitors (TKIs).  This study concluded that ponatinib was effective in heavily pretreated patients when administered in any phase of...

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Evaluating the long-term outcomes of radiotherapy added to standard therapy for men with metastatic prostate cancer.

Evaluating the long-term outcomes of radiotherapy added to standard therapy for men with metastatic prostate cancer.

Posted by on Sep 18, 2022 in Prostate cancer | 0 comments

In a nutshell The study investigated whether radiotherapy (RT) addedd to standard of care (SOC) treatment would be beneficial for men with metastatic (spread) prostate cancer (mPC). The study showed that adding RT to SOC improved the survival of men with low burden (defined as fewer than 10 lesions, no greater than 3cm in diameter) mPC. Some...

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Evaluating the effectiveness of laser photocoagulation plus anti-VEGF treatment in patients with diabetic eye disease.

Evaluating the effectiveness of laser photocoagulation plus anti-VEGF treatment in patients with diabetic eye disease.

Posted by on Sep 18, 2022 in Diabetes mellitus | 0 comments

In a nutshell This study evaluated the effectiveness of panretinal photocoagulation (PRP) plus intravitreal anti-VEGF treatment versus PRP alone for the treatment of patients with diabetic retinopathy (DR; diabetic eye disease). The data showed that PRP with anti-VEGF combination treatment improved vision without an increase in side effects...

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Evaluating the long-term effectiveness of ibrutinib–rituximab treatment versus standard chemoimmunotherapy in patients with chronic lymphocytic leukemia.

Evaluating the long-term effectiveness of ibrutinib–rituximab treatment versus standard chemoimmunotherapy in patients with chronic lymphocytic leukemia.

Posted by on Sep 18, 2022 in Leukemia | 0 comments

In a nutshell This study investigated the long-term effectiveness of ibrutinib (Imbruvica)–rituximab (Rituxan) (IR) treatment versus standard chemoimmunotherapy (CIT) in patients aged 70 or younger with previously untreated chronic lymphocytic leukemia (CLL). The data showed that the IT regimen significantly improved the survival outcomes compared...

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Evaluating the effectiveness and safety of adding PolyPepI1018 peptide vaccine to maintenance therapy in patients with microsatellite stable metastatic colorectal cancer.

Evaluating the effectiveness and safety of adding PolyPepI1018 peptide vaccine to maintenance therapy in patients with microsatellite stable metastatic colorectal cancer.

Posted by on Sep 18, 2022 in Colorectal cancer | 0 comments

In a nutshell This study evaluated the effectiveness and safety of adding PolyPepI1018 peptide vaccine to fluoropyrimidine/bevacizumab (Avastin) maintenance therapy in patients with microsatellite stable (MSS) metastatic colorectal cancer (mCRC). The data showed that PolyPEPI1018 added to maintenance therapy was safe and associated with specific...

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Evaluating the effectiveness and safety outcomes of administering radiotherapy at the same time with DCEP salvage chemotherapy in patients with multiple myeloma.

Evaluating the effectiveness and safety outcomes of administering radiotherapy at the same time with DCEP salvage chemotherapy in patients with multiple myeloma.

Posted by on Sep 17, 2022 in Multiple Myeloma | 0 comments

In a nutshell This study investigated the effectiveness and safety outcomes of administering radiotherapy (RT) at the same time as DCEP salvage chemotherapy in patients with unresponsive multiple myeloma (MM). This study concluded that RT administered at the same time with DCEP salvage chemotherapy was effective and well-tolerated by most of the...

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Evaluating the effectiveness of different types of acupuncture therapies in the treatment of rheumatoid arthritis.

Evaluating the effectiveness of different types of acupuncture therapies in the treatment of rheumatoid arthritis.

Posted by on Sep 17, 2022 in Rheumatoid Arthritis | 0 comments

In a nutshell This analysis compared the effectiveness of different acupuncture therapies combined with disease-modifying anti-rheumatic drugs (DMARDs) in the treatment of rheumatoid arthritis (RA). The data indicated that RA disease activity was most improved by combining electro-acupuncture and DMARDs while fire-needle or moxibustion plus DMARDs...

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