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Evaluating the effectiveness and safety of radium-223 dichloride treatment in real-world patients with metastatic castration-resistant prostate cancer.

Posted by Medivizor on Apr 30, 2023 in Prostate cancer | 0 comments

In a nutshell The study evaluated the effectiveness and safety of radium-223 dichloride (Xofigo) treatment in real-world patients with metastatic castration-resistant prostate cancer (mCRPC). The data showed that radium-223 dichloride treatment was well tolerated and reduced pain in real-world patients with mCRPC spread to the bone. Some...

Evaluating the effectiveness and safety of adding isatuximab to lenalidomide, bortezomib, and dexamethasone combination for patients with newly diagnosed transplantation-eligible multiple myeloma.

Posted by Medivizor on Apr 30, 2023 in Multiple Myeloma | 0 comments

In a nutshell This study evaluated the effectiveness and safety of adding isatuximab (Sarclisa) to lenalidomide (Revlimid), bortezomib (Velcade), and dexamethasone (Decadron) combination as induction therapy for patients with newly diagnosed transplantation-eligible multiple myeloma (MM). The data showed that the addition of isatuximab to lenalidomide,...

Evaluating the effectiveness and safety of a tumor bed boost after whole breast irradiation following breast-conserving surgery in patients with non-low-risk ductal carcinoma in situ.

Posted by Medivizor on Apr 23, 2023 in Breast cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of a tumor bed (where the tumor was present) boost after whole breast irradiation (WBI) following breast-conserving surgery (BCS) in patients with non-low-risk ductal carcinoma in situ (DCIS). The data showed that a tumor bed boost after WBI following BCS reduced local recurrence (return...

Evaluating the long-term outcomes of catheter-based renal artery denervation in patients with uncontrolled hypertension.

Posted by Medivizor on Apr 23, 2023 in Hypertension | 0 comments

In a nutshell This study reported the long-term outcomes of catheter-based renal artery denervation (CB-RD) in patients with resistant or uncontrolled hypertension [high blood pressure (BP)]. The data showed that over the long-term CB-RD was safe and had significantly greater reductions in BP and better BP control compared with a sham control in these...

Evaluating the effectiveness and safety of asciminib in real-world patients with chronic myeloid leukemia previously treated with ponatinib.

Posted by Medivizor on Apr 23, 2023 in Leukemia | 0 comments

In a nutshell This study evaluated the effectiveness and safety of asciminib (Scemblix) in real-world patients with chronic myeloid leukemia (CML) previously treated with ponatinib (Iclusig). The data showed that asciminib treatment had promising effectiveness in these patients. Some background CML is a type of cancer that starts in blood-forming...

Evaluating the effectiveness of degarelix with or without apalutamide before prostate surgery in patients with high-risk prostate cancer.

Posted by Medivizor on Apr 23, 2023 in Prostate cancer | 0 comments

In a nutshell This study evaluated the effectiveness of degarelix (Firmagon) with or without apalutamide (Erleada) before radical prostatectomy (RP; prostate surgery) in patients with high-risk prostate cancer (PC). The data showed that degarelix plus apalutamide significantly improved the pathological response in these patients. Some background...

Evaluating the effectiveness and safety of sacituzumab govitecan versus chemotherapy in patients with HR+, HER2– metastatic breast cancer.

Posted by Medivizor on Apr 23, 2023 in Breast cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of sacituzumab govitecan (Trodelvy; SG) compared to chemotherapy in patients with hormone receptor-positive (HR+)/HER2-negative (HER2-) metastatic breast cancer (BC). The data showed that SG significantly improved survival without cancer progression compared to chemotherapy in these...

Can autologous cell therapy improve severe diabetic foot disease?

Posted by Medivizor on Apr 15, 2023 in Diabetes mellitus | 0 comments

In a nutshell This study looked at the use of autologous cell therapy (ACT) to treat no-option chronic limb-threatening ischemia (NO-CLTI) in patients with diabetic patients. The study showed that compared to standard treatment, ACT resulted in a significant improvement in ischemia and food healing in these patients. Some background Diabetes...

Can BCT-100 be safely combined with low-dose cytarabine for older patients with acute myeloid leukemia that cannot receive intensive therapy?

Posted by Medivizor on Apr 15, 2023 in Leukemia | 0 comments

In a nutshell This study compared the effectiveness and safety of low-dose (LD) cytarabine (Ara-C; Cytosar-U) with recombinant arginase BCT-100 (BCT-100) to Ara-C alone in older patients with acute myeloid leukemia (AML) that were unsuitable for intensive therapy. The data showed that LD Ara-C (LDAC) combined with BCT-100 resulted in similar...

Evaluating the effectiveness and safety of a shorter dual antiplatelet therapy duration after coronary stenting in patients with acute or recent heart attack at high bleeding risk.

Posted by Medivizor on Apr 15, 2023 in Coronary artery disease | 0 comments

In a nutshell This study evaluated the effectiveness and safety of a shorter dual antiplatelet therapy (DAPT) duration after percutaneous coronary intervention (PCI) using drug-eluting stents (DES) in patients with acute or recent myocardial infarction (MI; heart attack) at high bleeding risk. The data showed that a shorter DAPT duration (1 month)...

Can low dose prednisolone as an add-on treatment reduce the economic burden for patients with rheumatoid arthritis?

Posted by Medivizor on Mar 26, 2023 in Rheumatoid Arthritis | 0 comments

In a nutshell This study evaluated the cost-effectiveness of low-dose prednisolone (Omnipred) at 5 mg daily in the treatment of patients with rheumatoid arthritis (RA) aged 65 years or more. The study found that a low dose of prednisolone was an effective add-on treatment for patients with RA based on similar or lower costs compared to a placebo for...

Evaluating the effectiveness and safety of trifluridine-tipiracil plus bevacizumab in patients with resistant metastatic colorectal cancer

Posted by Medivizor on Mar 26, 2023 in Colorectal cancer | 0 comments

In a nutshell This study evaluated the effectiveness and safety of the combination of trifluridine-tipiracil (Lonsurf) and bevacizumab (Avastin) in patients with unresponsive (refractory) metastatic colorectal cancer (mCRC) in a real-world setting. The main finding was that trifluridine–tipiracil plus bevacizumab was safe and effective in...

Evaluating the effectiveness and safety of radium-223 dichloride treatment in real-world patients with metastatic castration-resistant prostate cancer.

Evaluating the effectiveness and safety of adding isatuximab to lenalidomide, bortezomib, and dexamethasone combination for patients with newly diagnosed transplantation-eligible multiple myeloma.

Evaluating the effectiveness and safety of a tumor bed boost after whole breast irradiation following breast-conserving surgery in patients with non-low-risk ductal carcinoma in situ.

Evaluating the long-term outcomes of catheter-based renal artery denervation in patients with uncontrolled hypertension.

Evaluating the effectiveness and safety of asciminib in real-world patients with chronic myeloid leukemia previously treated with ponatinib.

Evaluating the effectiveness of degarelix with or without apalutamide before prostate surgery in patients with high-risk prostate cancer.

Evaluating the effectiveness and safety of sacituzumab govitecan versus chemotherapy in patients with HR+, HER2– metastatic breast cancer.

Can autologous cell therapy improve severe diabetic foot disease?

Can BCT-100 be safely combined with low-dose cytarabine for older patients with acute myeloid leukemia that cannot receive intensive therapy?

Evaluating the effectiveness and safety of a shorter dual antiplatelet therapy duration after coronary stenting in patients with acute or recent heart attack at high bleeding risk.

Can low dose prednisolone as an add-on treatment reduce the economic burden for patients with rheumatoid arthritis?

Evaluating the effectiveness and safety of trifluridine-tipiracil plus bevacizumab in patients with resistant metastatic colorectal cancer

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