In a nutshell This study examined the long-term outcomes of women who underwent tension-free vaginal tape-obturator (TVT-O) for stress incontinence. The authors determined that TVT-O was very effective in the long-term and was a safe option for the treatment of stress incontinence. Some background Vaginal sling procedures are the most common type...
Read MoreSearching for patients with hypertension after pregnancy to test the effects of non-steroidal anti-inflammatory drugs
In a nutshell The aim of this clinical trial is to test the effects of non-steroidal anti-inflammatory drugs on blood pressure in women with mild and severe hypertension after pregnancy. For patients with mild hypertension, the main outcome to be investigated is change in blood pressure throughout the study. For patients with severe hypertension, the...
Read MoreGestational diabetes: The effects of lifestyle interventions for mother and baby
In a nutshell This study analyzed the results of 15 separate studies to examine the effects of lifestyle interventions for gestational diabetes mellitus (GDM). Authors reported on a number of benefits for the mother and the baby following lifestyle interventions. Some background When a woman without diabetes develops high blood glucose levels...
Read MoreLong-term effects of stereotactic ablative radiotherapy for patients with NSCLC
In a nutshell The authors examined the long-term effects of stereotactic ablative radiotherapy (SABR) in treating patients with stage 1 non-small-cell lung cancer (NSCLC). They concluded that SABR is both safe and effective in the long-term. Some background SABR is a type of radiation used to treat inoperable early stage NSCLC. Studies have shown...
Read MoreLate effects of Hodgkin lymphoma in teenager and young adult survivors
In a nutshell This study investigated the amount of late complications that affect teenage and young adult Hodgkin lymphoma survivors. The authors concluded that these patients had higher risks of developing other cancers and getting sick compared to the general population. Some background Hodgkin lymphoma (HL) is the most common cancer among...
Read MoreComparing the effects of combined PI3K inhibitor/endocrine therapy versus endocrine therapy alone in ER-positive breast cancer
In a nutshell This study investigated whether the addition of the PI3K inhibitor pictilisib (Stemolecule GDC-0941) can increase the anti-tumor effects of anastrozole (Arimidex) in patients with estrogen receptor-positive (ER-positive) primary breast cancer (BC). Combined treatment with pictilisib (PIC)...
Read MoreThe beneficial effects of trastuzumab on locoregional control in HER2-positive breast cancer patients.
In a nutshell This study investigated the effects of trastuzumab (Herceptin) on the locoregional control (management in the area in which it arose) of patients with HER2-positive breast cancer (HER2+BC) following radiotherapy (RT). Trastuzumab administered alongside RT was found to be associated with a significantly reduced rate of locoregional...
Read MoreThe effects of dulaglutide in patients with type 2 diabetes
In a nutshell This article examined dulaglutide (Trulicity) in patients with type 2 diabetes (T2D). It found that dulaglutide was effective and tolerable. Some background T2D is a progressive disease. T2D may be controlled at first by lifestyle changes, like diet and exercise. However, eventually at least one, and often more, drugs may be...
Read MoreEffects of salt on the complications of type 2 diabetes
In a nutshell This study examined the link between salt (sodium) intake and complications of type 2 diabetes (T2D). The study found that high salt intake increased the risk of heart disease. Some background Heart disease, kidney disease, and vision problems are complications of T2D. It is recommended that patients with T2D decrease their...
Read MoreEffects of brentuximab-vedotin therapy in relapsed and refractory Hodgkin lymphoma
In a nutshell This study evaluated the effectiveness of brentuximab-vedotin therapy in relapsed- and refractory Hodgkin lymphoma patients. The authors concluded that the treatment was safe and effective. Some background Some Hodgkin lymphoma patients are either unresponsive to treatment (refractory disease), or relapse soon...
Read MoreThe effects of brentuximab vedotin on quality of life
In a nutshell This trial examined the quality-of-life (QOL) impact of an antibody therapy among patients who had already undergone standard treatment for relapsed- or refractory disease. The authors concluded that the treatment modestly decreased QOL during certain time periods only. Some background Hodgkin Lymphoma is generally highly...
Read MoreLate effects of treatment in Hodgkin lymphoma
In a nutshell This article summarized some of the possible late effects of Hodgkin lymphoma treatment. Some background The standard treatment options for Hodgkin lymphoma are radiation and chemotherapy. These treatments have led to very high remission rates (no sign of disease) in many patients. Radiation and chemotherapy have also been associated...
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