In a nutshell The study evaluated the long-term effectiveness and safety of Ofatumumab (Arzerra) and chlorambucil (Leukeran) (CHL) in patients with previously untreated chronic lymphocytic leukemia (CLL). The authors found that the combination therapy safely improved clinical outcomes in such patients in 5 years, compared to chlorambucil alone. Some...
Read MoreThe effects of hydroxychloroquine and imatinib on treatment outcomes in patients with chronic myeloid leukemia
In a nutshell The study evaluated the combined effects of imatinib (IM; Gleevec) and hydroxychloroquine (HCQ; Plaquenil) in patients with chronic-phase chronic myeloid leukemia (CP-CML) and residual leukemic stem cells. The authors found that this combination safely and moderately improved treatment outcomes in such patients compared to IM alone. Some...
Read MoreDoes immune cell boosting drug G-CSF reduce the effects of chemotherapy in different cancers?
In a nutshell This study examined the effects of granulocyte colony-stimulating factor (G-CSF) given as a preventative measure in patients with high- and medium-risk cancer receiving chemotherapy. The results showed that preventative G-CSF allowed more patients to complete chemotherapy treatment and lowered patients’ chances of developing secondary...
Read MoreDoes immune cell boosting drug G-CSF reduce the effects of chemotherapy in different cancers?
In a nutshell This study examined the effects of granulocyte colony-stimulating factor (G-CSF) given as a preventative measure in patients with high- and medium-risk cancer receiving chemotherapy. The results showed that preventative G-CSF allowed more patients to complete chemotherapy treatment and lowered patients’ chances of developing secondary...
Read MoreDoes immune cell boosting drug G-CSF reduce the effects of chemotherapy in different cancers?
In a nutshell This study examined the effects of granulocyte colony-stimulating factor (G-CSF) given as a preventative measure in patients with high- and medium-risk cancer receiving chemotherapy. The results showed that preventative G-CSF allowed more patients to complete chemotherapy treatment and lowered patients’ chances of developing secondary...
Read MoreDoes immune cell boosting drug G-CSF reduce the effects of chemotherapy in different cancers?
In a nutshell This study examined the effects of granulocyte colony-stimulating factor (G-CSF) given as a preventative measure in patients with high- and medium-risk cancer receiving chemotherapy. The results showed that preventative G-CSF allowed more patients to complete chemotherapy treatment and lowered patients’ chances of developing...
Read MoreCardiovascular effects of chemotherapy after colorectal cancer surgery
In a nutshell This study investigated the cardiovascular effects of chemotherapy after colorectal cancer (CRC) surgery. Researchers suggested that this treatment increases the stiffness of blood vessels in patients with CRC. Some background Colorectal cancer is a major cause of cancer mortality. However, the mortality rate has decreased in the...
Read MoreWhat are the long-term effects of treatment with a biological drug versus chemotherapy for patients with advanced non-small cell lung carcinoma?
In a nutshell This study compared the long-term effects of biological drug pembrolizumab (Keytruda) with chemotherapy drug docetaxel (Taxotere) in patients with advanced non-small cell lung carcinoma (NSCLC). The study found that pembrolizumab increased survival and had fewer side effects than docetaxel. Some background Patients with advanced...
Read MoreEvaluating the effects of smoking during the first trimester of pregnancy
In a nutshell This study looked at the pregnancy outcomes of women who smoked only during their first trimester. This study found that women who quit smoking early in pregnancy had a lower risk of having a baby with a low birth weight. Some background Tobacco smoke contains numerous chemicals that may be harmful during pregnancy, including nicotine...
Read MoreEvaluating the effects of venetoclax and obinutuzumab in patients with untreated chronic lymphocytic leukemia
In a nutshell The study evaluated the treatment benefits of venetoclax (Venclexta) and obinutuzumab (Gazyva) in patients with untreated chronic lymphocytic leukemia (CLL) and coexisting medical conditions. The main finding was that the combination therapy improved outcomes in these patients. Some background Most patients with CLL are older...
Read MoreEffects of TKIs on glucose and lipid metabolism in patients with chronic phase chronic myeloid leukemia
In a nutshell This study aimed to evaluate glucose (blood sugar) and lipid (fat) metabolism between dasatinib, nilotinib, and imatinib in patients with chronic-phase chronic myeloid leukemia. This study concluded that dasatinib and nilotinib had a negative impact on glucose and lipid...
Read MoreWhat are the effects of salvage stereotactic radiotherapy (SSRT) in prostate cancer relapse after prostate surgery?
In a nutshell This study investigated the effects of salvage stereotactic radiotherapy (SSRT) in patients with prostate bed recurrence after prostate surgery. The main finding was that SSRT was effective at curing or delaying prostate cancer recurrence. Some background Almost 30% of men who undergo radical prostatectomy (complete removal of the...
Read More
