In a nutshell This study reviewed treatment options for older patients newly diagnosed with classical Hodgkin lymphoma (cHL). It found that treatments including brentuximab vedotin (BV: Adcetris) are effective in this age group and that avoiding bleomycin (Blenoxane) prevents lung damage. Some background Around 20% of patients diagnosed with cHL...
Read MoreCurrent treatment for advanced classical Hodgkin lymphoma
In a nutshell This review summarizes current treatment options of advanced classical Hodgkin lymphoma. It found that PET-scan based treatment minimizes long-term side effects and that both ABVD and eBEACOPP are useful chemotherapy regimens. Some background Classical Hodgkin lymphoma (cHL) is a cancer of white blood cells. If cancerous...
Read MoreEvaluating brentuximab vedotin for elderly patients with hard to treat Hodgkin lymphoma
In a nutshell This study evaluated the safety and effectiveness of brentuximab vedotin (Adcetris) in elderly patients with relapsed or unresponsive Hodgkin lymphoma (HL). This study found that this treatment was effective, although frail patients may be at higher risk for side effects. Some background Most patients with HL respond to front-line...
Read MoreRisk adjusted treatment of children with non-T cell acute lymphoblastic leukemia
In a nutshell The study reported the outcomes of children with non-T cell acute lymphoblastic leukemia (ALL) treated with risk-adjusted therapy. The main finding was that patients with standard-risk (SR) ALL had improved survival without cancer-related events. Some background ALL-97 was the first clinical trial performed on Japanese children with ALL....
Read MoreHigh-intensity exercise rehabilitation improves sleep disorder outcomes in patients with Parkinson’s disease
In a nutshell This study investigated whether high-intensity exercise rehabilitation (HIER) improved sleep in patients with Parkinson's disease (PD). Researchers suggested that HIER improves sleep in these patients. Some background Parkinson's disease (PD) is a progressive brain disorder. The brain cells lose their abilities to control...
Read MoreEvaluating bortezomib consolidation or maintenance for patients with multiple myeloma
In a nutshell This study evaluated the safety and effectiveness of consolidation and maintenance regimens containing bortezomib (Velcade) for multiple myeloma (MM). This study concluded that consolidation therapy with bortezomib improved survival without tumor growth or spread. Some background Multiple myeloma is a type of cancer of the bone...
Read MoreReviewing treatment options for patients with high-risk prostate cancer
In a nutshell This article reviewed treatment options for patients with high-risk prostate cancer. Some background Prostate cancer is a cancer that starts in the prostate gland. There are different types of treatment for patients with prostate cancer. Treatment choice depends on disease stage or whether the cancer has spread to other parts of the...
Read MoreIs tamsulosin and tadalafil a safe and effective treatment for lower urinary tract symptoms?
In a nutshell This study aimed to compare the effectiveness and safety of tamsulosin (Flomax) versus tamsulosin and tadalafil (Cialis) for the treatment of lower urinary tract symptoms (LUTS). The main finding was that the combination treatment appeared to improve LUTS more than treatment with tamsulosin alone, with no difference in side effects. Some...
Read MoreTreating chronic myeloid leukemia with dasatinib
In a nutshell This study aimed to investigate the long-term outcomes of dasatinib treatment for patients with chronic myeloid leukemia. This study concluded that dasatinib is safe and provides positive long-term outcomes for these patients. Some background Dasatinib (Sprycel) is a targeted therapy...
Read MoreFunctional electrical stimulation improves balance in stroke survivors
In a nutshell This study investigated the effects of balance training with functional electrical stimulation (FES) to treat stroke survivors. Researchers suggested that this treatment improves balance and muscle activation in patients with stroke. Some background Every year, more than 795,000 people in the US have a stroke. It happens when the blood...
Read MoreIs mirabegron a safe and effective treatment for overactive bladder symptoms?
In a nutshell This paper investigated the effectiveness and safety of mirabegron (Myrbetriq) for the treatment of symptoms of overactive bladder (OAB). Mirabegron appeared to be safe and effective for the treatment of OAB symptoms. Some background OAB is characterized by symptoms such as experiencing incontinence (urine leakage), having a strong urge...
Read MoreEvaluating pembrolizumab plus R-CHOP chemotherapy for patients with untreated diffuse large B-cell lymphoma
In a nutshell This study evaluated the safety and effectiveness of pembrolizumab (Keytruda) plus R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone) chemotherapy for patients with diffuse large B-cell lymphoma (DLBCL). This study concluded that pembrolizumab can be safely added to R-CHOP, with improved survival outcomes. Some...
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