In a nutshell This study investigated the effect of baricitinib (Olumiant) on biomarkers in the blood, which indicate a state of joint destruction in patients with moderate to severe rheumatoid arthritis (RA). The study showed that baricitinib reduced these biomarkers and resulted in decreased RA symptoms. Some...
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In a nutshell This study investigated the long-term effectiveness and safety of certolizumab pegol (Cimzia) in patients with rheumatoid arthritis (RA) from a real-world practice. They found that this medication was safe and patients had a sustained response. Some background Rheumatoid arthritis (RA) is a chronic condition. It is...
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In a nutshell This study investigated the neutrophil-to-lymphocyte ratio (NLR) as an indicator of infection in patients with rheumatoid arthritis (RA) treated with tocilizumab (Actemra). They found that the NLR is an accurate indicator of infection in these patients. Some background Rheumatoid arthritis (RA) is a chronic condition. It...
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In a nutshell This study investigated if biological disease-modifying anti-rheumatic drugs (bDMARDs) affect diabetes risk in patients with rheumatoid arthritis (RA). They found that bDMARD use was associated with lower rates of diabetes in these patients. Some background Rheumatoid arthritis (RA) is a chronic condition. It is caused by...
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In a nutshell This study investigated the effectiveness and safety of upadacitinib (Rinvoq) to abatacept (Orencia) for patients with rheumatoid arthritis (RA). The study showed that upadacitinib was more effective in lowering the disease activity score (DAS28) and in decreasing symptoms, but had more side...
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In a nutshell This study investigated if weight changes increase the risk of cardiovascular events (CVEs) in patients with rheumatoid arthritis (RA). They found that a 10% increase or decrease in weight increased the risk of CVEs in these patients. Some background Rheumatoid arthritis (RA) is a chronic condition. It is caused...
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In a nutshell This study investigated the effect of tocilizumab (Actemra) on disease-progression in young patients with systemic juvenile idiopathic arthritis (sJIA) and polyarticular-course juvenile idiopathic arthritis (pcJIA). The data showed that tocilizumab may slow down the progression of sJIA and pcJIA in digital...
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In a nutshell This study investigated the impact of dietary supplements and diet changes on disease activity score (DAS) in patients with rheumatoid arthritis (RA). The study showed that some diet types like the Mediterranean diet, some spices and supplements may have positive effects on RA symptoms. Some background RA causes...
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In a nutshell This study investigated the effects of a rehabilitation program on pain, quality of life (QoL), and c-reactive protein (CRP) values for patients with rheumatoid arthritis (RA) and different levels of disease activity score (DAS). The study found that a rehabilitation program significantly...
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In a nutshell This study investigated quality of life (QoL) with tocilizumab (Actemra) in children with juvenile idopathic arthritis (JIA). They found that tocilizumab improved QoL in these patients. Some background Juvenile idiopathic arthritis (JIA) is a chronic condition. It is caused by inflammation. Children usually develop...
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In a nutshell This study analyzed the risk of infections for patients with rheumatoid arthritis (RA) treated with baricitinib (Olumiant). The study showed that there is a higher risk of non-serious infections in patients taking baricitinib. Some background RA is a chronic inflammatory auto-immune disease affecting the whole...
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In a nutshell This study observed the effects of physical activity on patients with chronic inflammatory diseases such as rheumatoid arthritis (RA) by using the supervision of a physiotherapist (PT) and additional digital monitoring. It showed that the multi-component procedures can help improve pain and the level of daily activity in these...
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