In a nutshell The authors assessed predictive factors in the progression of rheumatoid arthritis (RA) 1 year after diagnosis. Some background In RA, high levels of immune system proteins are generated. This causes inflammation, leading to chronic pain and structural damage in the joints. An X-ray based imaging technique called...
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In a nutshell The authors analyzed the effect of mechanical stress on the progression of rheumatoid arthritis (RA) in the hands. Some background In RA, high levels of immune system proteins are generated. This causes inflammation, leading to chronic pain and structural damage in the joints. An X-ray based imaging technique called...
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In a nutshell The authors analyzed the safety and effectiveness of certolizumab pegol (Cimzia) in combination with methotrexate (Trexall) in the treatment of rheumatoid arthritis (RA). Some background In RA, high levels of immune system proteins are generated. This causes inflammation, leading to chronic...
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In a nutshell The authors analyzed the correlation between muscle strength and physical function in women with systemic lupus erythematosus (SLE- a disease of the immune system). Some background In SLE, the immune system mistakenly attacks normal, healthy tissues. SLE can affect the skin, joints, kidney, brain and other organs. There...
Read MoreIn a nutshell The authors compared the effectiveness and safety of SB4, a biological variant of etanercept (Enbrel), to etanercept alone in patients with rheumatoid arthritis (RA). Some background In RA, high levels of immune system protein are generated, which causes inflammation. This can lead to...
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In a nutshell The authors analyzed the occurrence of treatment-related side effects in rheumatoid arthritis (RA) and the factors that cause discontinuation of such treatments. Some background In RA, high levels of immune system proteins are generated. This causes inflammation, leading to chronic pain. Disease-modifying...
Read MoreIn a nutshell The authors analyzed the effect of dose reduction in rheumatoid arthritis patients (RA) in remission (disease recovery). Some background Disease-modifying antirheumatic drugs (DMARDs) are safe and effective treatments in patients with RA. DMARDs can be chemical or biological. The objective of these treatments is to achieve...
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In a nutshell The authors evaluated the risks of developing depression in patients with rheumatoid arthritis (RA). Some background In RA, high levels of immune system proteins are generated, which causes inflammation in the joints. This leads to long-lasting pain. Several studies have reported that, due to the increase in pain...
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In a nutshell The authors compared the safety and long-term effectiveness of subcutaneous (injected under skin) tocilizumab (Actemra) to intravenous (injected through veins) tocilizumab in patients with rheumatoid arthritis (RA). Some background In RA, the body's immune system mistakenly attacks the...
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In a nutshell This study examined the effect of yoga on activity in arthritis patients. Some background Physical activity is important in arthritis patients as it maintains joint stability and range of motion and also reduces pain and fatigue. However, the joint pain and stiffness in patients can limit physical activity. 44% of arthritis...
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In a nutshell This study examined the factors that predict changes in weight in rheumatoid arthritis patients. Some background In rheumatoid arthritis (RA), the immune system begins to attack the healthy joints, causing pain, inflammation, and destruction of the joints. RA patients who have a low body mass index (BMI– measure of body fat...
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In a nutshell This study examined the effectiveness and safety of tocilizumab and leflunomide combination therapy. Some background Methotrexate (Trexall) is a drug used to treat patients with rheumatoid arthritis (RA). Methotrexate is often combined with a biological therapy (drugs that block the immune system) such as tocilizumab (Actemra). This...
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