In a nutshell This study investigated various remission parameters in rheumatoid arthritis (RA) patients treated with abatacept (Orencia) plus methotrexate (Trexall). Some background In RA, the immune system begins attacking healthy tissues the way it normally attacks viruses or bacteria. This can cause inflammation, leading to chronic pain....
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In a nutshell The authors analyzed the effect of tofacitinib (Xeljanz) in controlling inflammation of the synovium (joint lining) in rheumatoid arthritis (RA). Some background In RA, the immune system begins attacking healthy tissue the way it normally attacks viruses or bacteria. This can cause inflammation, leading to chronic...
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In a nutshell The authors aimed to compare the effectiveness of rituximab (Rituxan) with a tumor necrosis factor inhibitor in the treatment of rheumatoid arthritis. Some background In rheumatoid arthritis (RA), the immune system begins attacking healthy tissue the way it normally attacks viruses or bacteria. This can cause...
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In a nutshell The authors compared the duration of time from initiation to discontinuation of therapy between three drugs: infliximab (Remicade), adalimumab (Humira) and etanercept (Enbrel) in rheumatoid arthritis (RA). Some background In RA, the immune system attacks healthy tissues instead of viruses or bacteria....
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In a nutshell This study examined whether treatment with biological therapy can reduce the risk of cardiovascular disease in rheumatoid arthritis patients. Some background Patients with rheumatoid arthritis (RA) have a higher risk of developing cardiovascular disease (CVD). CVD is the narrowing or blockage of blood vessels and can lead...
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In a nutshell The authors analyzed the effectiveness of rituximab (Rituxan – a biological therapy) for the treatment of rheumatoid arthritis (RA) patients previously treated with another biological therapy. Some background In RA, high levels of immune system proteins are generated. This causes inflammation, leading to...
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In a nutshell The authors evaluated the safety and effectiveness of certolizumab pegol (Cimzia) in patients with low to moderate rheumatoid arthritis (RA). Some background In RA, high levels of immune system proteins are generated. This causes inflammation, leading to chronic pain. Disease-modifying antirheumatic drugs...
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In a nutshell The authors investigated the effect of etanercept (Enbrel) dose change on patients with rheumatoid arthritis (RA). Some background In RA, high levels of immune system protein are generated, which causes inflammation, leading to chronic pain. Several studies indicated that etanercept in combination...
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In a nutshell The authors evaluated the effect of tofacitinib (Xeljanz) on kidney function in rheumatoid arthritis (RA) patients. Some background In RA, high levels of immune system proteins are generated. This causes inflammation, leading to chronic pain and joint damage. In several phase III clinical...
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In a nutshell The authors evaluated the progression of joint destruction in wrist and feet rheumatoid arthritis (RA). Some background In RA, high levels of immune system proteins are generated. This causes inflammation, leading to chronic pain and structural joint damage. In the early stage of the disease, joint inflammation can affect...
Read MoreIn a nutshell The authors compared the effectiveness and safety of SB2, a biological variant of infliximab (Remicade) — the original biological product, to infliximab itself in patients with moderate to severe rheumatoid arthritis (RA). Some background In RA, high levels of immune system protein are generated...
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In a nutshell The authors determined if patients with rheumatoid arthritis (RA) are at a greater risk of experiencing severe pancreatitis (inflammation of the pancreas – a gland in the stomach). Some background In RA, high levels of immune system proteins are generated. This causes inflammation, leading to chronic pain and...
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