In a nutshell This study investigated whether men with rheumatoid arthritis are at an increased risk of developing osteoporosis. They found that men with rheumatoid arthritis are twice as likely to develop osteoporosis compared to healthy individuals. Some background Treatment of rheumatoid arthritis (RA) involves medications...
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Upadacitinib: a safe and effective medication to treat rheumatoid arthritis?
In a nutshell This study investigated the safety and effectiveness of upadacitinib for the treatment of rheumatoid arthritis. They found that upadacitinib is a safe and effective treatment for RA. Some background Disease-modifying anti-rheumatic drugs (DMARDs) are one of the standard medications to treat rheumatoid arthritis (RA). Biological...
Read MoreDo glucocorticoid drugs affect bone density in patients with rheumatoid arthritis?
In a nutshell This study investigated if glucocorticoid drugs affect bone mineral density in patients with rheumatoid arthritis. They found that the use of glucocorticoid drugs was not associated with changes in bone mineral density. Some background To treat rheumatoid arthritis (RA), patients are prescribed medication to reduce inflammation. One...
Read MoreSustaining remission in rheumatoid arthritis and identifying suitable patients for tapered treatment
In a nutshell This study examined the features of long-term disease remission in patients with rheumatoid arthritis (RA) on reduced treatment. The study concluded that disease activity, synovitis, rheumatoid factor and a history of smoking are associated with treatment failure. Some background Biological (b)DMARDs (disease-modifying...
Read MoreSarilumab versus adalimumab in the treatment of rheumatoid arthritis – a patient’s perspective
In a nutshell This study compared sarilumab and adalimumab for the treatment of rheumatoid arthritis (RA). They found that sarilumab–treated patients reported greater improvements in overall health and disability, quality of life and pain scores. Some background Treatment of rheumatoid arthritis (RA) involves medications to reduce...
Read MoreDo glucocorticoid drugs increase the risk of adverse events in patients with rheumatoid arthritis?
In a nutshell This study investigated adverse events associated with glucocorticoid medications in patients with rheumatoid arthritis. The study found that patients with RA have an increased incidence of adverse events associated with the use of glucocorticoids. Some background Treatment of rheumatoid arthritis (RA) involves taking...
Read MoreNon-steroidal anti-inflammatory drugs (NSAIDs) in rheumatoid arthritis: a potential risk factor for stroke or heart attack?
In a nutshell This study investigated if non-steroidal anti-inflammatory drugs (NSAIDs) increase the risk of heart attack or stroke in patients with rheumatoid arthritis (RA). They found that non-selective NSAIDs were associated with an increased risk of both stroke and heart attack in RA patients. Some background One type of medication used to...
Read MoreAssessing cancer risk in patients using disease-modifying drugs and corticosteroids to treat rheumatoid arthritis
In a nutshell This study investigated the risk of skin cancer in patients taking disease-modifying drugs (DMARDs) and corticosteroids to treat rheumatoid arthritis (RA). They concluded that certain DMARDs and corticosteroids are associated with an increased risk of non-melanoma skin cancer. Some background Rheumatoid arthritis (RA) is a...
Read MoreJuvenile arthritis: can we predict disease progression and improve treatment outcomes?
In a nutshell This study investigated the factors that may predict disease progression in patients with juvenile idiopathic arthritis (JIA). They found that prediction models based on clinical factors can predict the likelihood of achieving remission and the level of disability long-term. Some background Juvenile idiopathic arthritis (JIA) is a...
Read MoreWhat predicts rapid disease progression in patients with early rheumatoid arthritis?
In a nutshell This study investigated the factors that may predict disease progression in patients with early rheumatoid arthritis. They found that history of smoking and elevated inflammation may predict rapid radiological progression. Some background Rheumatoid arthritis is a condition that causes painful swelling and inflammation in the...
Read MoreDoes reduced muscle density contribute to physical dysfunction in rheumatoid arthritis?
In a nutshell This study investigated the effects of low muscle density on physical strength and function in patients with rheumatoid arthritis. The study concluded that low muscle density was associated with greater disease activity, reduced muscle strength and poorer physical function. Some background Rheumatoid arthritis (RA) is a...
Read MoreImproving function and reducing pain in arthritis: the importance of footwear
In a nutshell This study investigated the effectiveness of footwear on foot pain and function in patients with foot and ankle arthritis. The authors determined that footwear interventions were associated with reduced pain and improved function and mobility in patients with arthritis of the foot and ankle. Some background Arthritis causes...
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