In a nutshell This study investigated if etanercept is effective at treating flare-ups in patients with rheumatoid arthritis. They found that etanercept reduces disease activity following flare-ups in these patients. Some background Rheumatoid arthritis (RA) is a long-term condition caused by inflammation. In RA, inflammation causes the damage to...
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Does poor diet increase inflammation in rheumatoid arthritis?
In a nutshell This study investigated if diet quality was associated with disease activity in patients with rheumatoid arthritis. They found that patients with poor diet had higher levels of inflammation. Some background Rheumatoid arthritis (RA) is a chronic (long-term) condition. It is an auto-immune disease. In RA, the immune system attacks...
Read MoreRituximab and the risk of infections in rheumatoid arthritis
In a nutshell This study investigated the long-term safety of rituximab (Rituxan) in patients with rheumatoid arthritis (RA). They found that the rate of infections did not increase with prolonged rituximab treatment. Some background Treating rheumatoid arthritis (RA) involves taking medication to reduce symptoms. RA is caused by inflammation and is...
Read MoreSleep impairment in rheumatoid arthritis – understanding the negative impact and treatment strategies
In a nutshell This study reviewed sleep impairment and its treatment strategies for patients with rheumatoid arthritis (RA). Some background Sleep quality and duration is important for overall health. Evidence suggests that sleep impairment can contribute to many diseases including rheumatoid arthritis (RA). Patients with RA may experience insomnia...
Read MoreLong-term treatment with csDMARDs in rheumatoid arthritis: results from 10-year follow-up
In a nutshell This study investigated the long-term effectiveness of csDMARDs in patients with rheumatoid arthritis (RA). They found that csDMARDs are effective at managing RA symptoms long-term. Some background Managing rheumatoid arthritis (RA) involves taking medication to reduce inflammation. The aim is to achieve the lowest level of disease...
Read MoreCanakinumab – an effective and safe long-term treatment for systemic juvenile idiopathic arthritis?
In a nutshell This study investigated the long-term safety and effectiveness of canakinumab (Ilaris) in patients with systemic juvenile idiopathic arthritis (sJIA). They found that this drug improved sJIA symptoms and was well tolerated in the long-term. Some background Systemic juvenile idiopathic arthritis (sJIA) is a condition that affects...
Read MorePreterm delivery in patients with rheumatoid or idiopathic arthritis: what are the risks?
In a nutshell This study investigated the causes of preterm delivery (PTD) in women with inflammatory arthritis (IA). They found that corticosteroids and disease activity were among the factors that increased the risk of PTD in women with IA. Some background Rheumatoid (RA) and juvenile idiopathic arthritis (JIA) are types of IA. Treatment options for...
Read MoreCombination vs. monotherapy: which treatment strategy is effective in the long-term?
In a nutshell This study investigated if treatment with just biological drugs or a combination of biological and synthetic drugs is effective long-term in rheumatoid arthritis (RA). They found that combination treatment is associated with a lower risk of treatment failure. Some background Treating rheumatoid arthritis (RA) involves taking medication...
Read MoreTocilizumab for rheumatoid arthritis: should treatment be extended to every 6 weeks?
In a nutshell This study investigated the effects of tocilizumab (Actemra) treatment every 6 weeks in patients with rheumatoid arthritis. They found that tocilizumab every 6 weeks maintains low disease activity for most patients. Some background Rheumatoid arthritis (RA) is a chronic (long-term) illness. The aim of RA treatment is to...
Read MoreCan treatment with certolizumab pegol (CZP) improve disease symptoms in patients with rheumatoid arthritis?
In a nutshell This study investigated if certolizumab pegol (Cimzia) in combination with methotrexate (Trexall) can reduce disease activity in patients with rheumatoid arthritis (RA). They found that this treatment combination was safe and improved RA symptoms. Some background Rheumatoid arthritis (RA) is a condition caused by an overactive immune...
Read MoreObesity and Rheumatoid arthritis: is disease progression worse and does adalimumab improve symptoms?
In a nutshell This study investigated if the response to rheumatoid arthritis (RA) treatment is worse in obese patients. They found that obese patients with RA have a worse clinical response than non-obese patients do. Some background Rheumatoid arthritis (RA) is an inflammatory condition. Fat tissue contains high levels of inflammatory chemicals....
Read MoreWhat signs predict a flare in rheumatoid arthritis?
In a nutshell This study investigated if there are factors that predict if a patient will have a flare in rheumatoid arthritis (RA). They found that patients with worse disease activity, functional disability, and quality of life were more likely to experience flares. Some background Rheumatoid arthritis (RA) is a chronic (long-term),...
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