In a nutshell This study investigated if vitamin D levels and disease activity are linked in juvenile idiopathic arthritis (JIA). They found that low vitamin D levels were associated with higher disease activity. Some background Juvenile idiopathic arthritis (JIA) is caused by inflammation in the joints. The cause of JIA is unknown. In JIA, the...
Read MoreIn a nutshell This clinical study will investigate the use of daily ultrasound for the treatment of rheumatoid arthritis (RA). The main outcome of interest is an improvement in RA disease activity. The trial will take place in Minneapolis, Minnesota, United States. The details Rheumatoid arthritis (RA) is a long-term condition caused...
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In a nutshell This study investigated three treatment strategies to achieve remission in patients with juvenile idiopathic arthritis (JIA). They found that all treatment strategies were effective in achieving remission in JIA. Some background Juvenile idiopathic arthritis (JIA) is caused by inflammation. It causes painful swelling in the joints...
Read MoreIn a nutshell This study investigated intensive treatment to achieve remission in rheumatoid arthritis (RA). They found that intensive treatment was effective at achieving remission. Some background Rheumatoid arthritis (RA) is a long-term condition. It is caused by painful inflammation in the joints. To treat RA, patients are prescribed drugs...
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In a nutshell This study investigated if reducing the dose of baricitinib (BCB; Olumiant) maintained low disease activity (LDA) in rheumatoid arthritis (RA). They found that a lower dose of BCB maintained LDA in some patients while the others could be rescued by switching to the original dose. Some background Rheumatoid...
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In a nutshell This study investigated if emotional health affects pain in patients with rheumatoid arthritis (RA). They found that emotional health, along with physical state can have an effect on pain in RA. Some background Rheumatoid arthritis (RA) is a long-term condition. It leads to painful swelling and inflammation in the joints. As...
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In a nutshell This study reviewed information on the use of tofacitinib (Xeljanz) for the treatment of rheumatoid arthritis (RA). They found that tofacitinib is effective and well-tolerated for patients with RA. Some background Tofacitinib (TFB) is a new drug to treat rheumatoid arthritis (RA). It blocks a type of enzyme...
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In a nutshell This study investigated if tocilizumab (TCZ; Actemra) increases cardiovascular (CVD) risk in patients with rheumatoid arthritis (RA). They found that CVD risk associated with TCZ was similar to other biological drugs. Some background Rheumatoid arthritis (RA) is caused by excessive inflammation. Inflammation leads to pain and...
Read MoreIn a nutshell This phase 2 trial will evaluate the effects of ABBV-105, taken alone or in combination with upadacitinib for the treatment of rheumatoid arthritis (RA). The main outcome to be measured will be an improvement in disease activity. The details Rheumatoid arthritis (RA) is a condition caused by excessive inflammation. Patients...
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In a nutshell This study investigated if exercise and anti-TNF medication can improve cardiovascular health (CVH) in patients with rheumatoid arthritis (RA). They found that combining exercise and anti-TNF medication improved CVH in these patients. Some background Rheumatoid arthritis (RA) is a long-term condition caused by inflammation in the joints....
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In a nutshell This study investigated the risk of heart failure in patients treated with either etanercept (Enbrel) or abatacept (Orencia) for rheumatoid arthritis (RA). They found that these drugs do not increase the risk of heart failure. Some background Rheumatoid arthritis (RA) is caused by chronic inflammation. This causes pain and swelling...
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In a nutshell This study investigated the safety of baricitinib (Olumiant) for the treatment of rheumatoid arthritis (RA). They found that baricitinib was well tolerated in patients with moderate-severe RA. Some background Rheumatoid arthritis (RA) is treated with medications to reduce inflammation. In RA, inflammation causes painful swelling and...
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