In a nutshell This study examined if vascular-targeted photodynamic therapy (VTPT), or active surveillance is more effective in the treatment of low-risk prostate cancer. This study concluded that patients who received VTPT were less likely to require radical therapy compared to those who underwent active surveillance. Some background...
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In a nutshell This study examined the safety and effectiveness of slow-release leuprolide mesylate (LM) administered by injection under the skin (leuprolide mesylate subcutaneous injectable suspension or LMIS), in the treatment of advanced prostate cancer. This study concluded that this medication is safe and effective in the treatment of advanced...
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In a nutshell This study examined stereotactic body radiotherapy (SBRT) as a treatment for advanced prostate cancer. This study concluded that SBRT may be effective in the treatment of these patients. Some background Oligometastatic prostate cancer is cancer that is no longer confined to the prostate gland. However, it has not yet become...
Read MoreIn a nutshell This trial is looking at blocking androgens (male sex hormones) with different medications in men with raised PSA (a blood marker of prostate cancer) levels after prostate surgery. The main outcome to be measured will be the length of time the patients survive without the cancer progressing. This study is being conducted in the United...
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In a nutshell This trial is examining how effective different treatments are at shrinking the prostate cancer before surgery. The main outcomes to be measured will be a complete response (complete disappearance of cancer) and minimal residual disease (almost undetectable cancer). This study is being conducted in Massachusetts and New York, the United...
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New: Thanks to InVideo, we have a video version of the post below. Check it out at bottom of the post. Incredible immunotherapy responses in some cancers, but not in others, have puzzled the research community. What is it about some cancers that allows the immune system to be activated? Why are some cancers able to evade the immune system even when...
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In a nutshell This trial is examining the effectiveness of radiation therapy, in treating patients with high-risk prostate cancer features after radical prostatectomy (surgery to remove the prostate gland). The main outcome to be measured will be freedom from failure. Failure is evidence that the cancer has returned. Patients will be followed up for 5...
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In a nutshell This study examined if exposure to certain environmental chemicals is linked to prostate cancer recurrence. This study concluded that environmental estrogens may increase the risk of prostate cancer recurrence. Some background Prostatectomy (surgical removal of the prostate) is a treatment option for localized (has not spread)...
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In a nutshell This study investigated the effectiveness of prostate radiotherapy (RT) in prostate cancer (PC). They found that prostate RT may improve survival in men with PC and fewer than 5 bone metastasis (cancer that has spread to the bones). Some background Prostate cancer (PC) is a common and treatable cancer in men. One common type...
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In a nutshell This study examined the impact of different prostate cancer treatments on quality of life. This study concluded stereotactic body radiotherapy (SBRT) and active surveillance resulted in a similar quality of life in the long term. Some background Radiation therapy (RT) is a common treatment for localized (confined) prostate cancer....
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In a nutshell This study examined if anti-androgen therapy for prostate cancer is associated with depression. This study concluded that the risk of depression is increased in these patients. Some background Anti-androgen therapy or androgen deprivation therapy (ADT) is commonly used in the treatment of prostate cancer. Androgens (such as...
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In a nutshell This trial is examining the effectiveness of radical prostatectomy, in newly diagnosed advanced prostate cancer. The main outcome to be measured will be survival without the cancer worsening. This trial is recruiting in the United States. The details Androgens can cause the growth of prostate cancer cells. Antiandrogen therapy (ADT) may...
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