In a nutshell This study evaluated the effectiveness and safety of the ND0612 delivery system of levodopa/carbidopa (Sinemet) in patients with Parkinson's disease (PD). The authors showed that the system was well-tolerated and safe and that it reduced the fluctuations of the levodopa plasma levels. Some background Parkinson's...
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In a nutshell In this work, the authors evaluated the effectiveness of safinamide (Xadago) on mood in patients with Parkinson's disease (PD). The study showed that safinamide improved PD patients' mood and emotional wellbeing at 6 months. Some background Parkinson's disease (PD) is the second most common...
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In a nutshell This study looked at the effects of long-term physiotherapy (6 months or more) on patients with Parkinson's disease. It found that patients doing long-term physiotherapy had fewer symptoms during the "off" medication phase, and needed lower doses of levodopa (Sinemet) to manage their symptoms compared to patients not...
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In a nutshell This study looked at how motor symptoms progressed in patients with Parkinson's disease (PD), before and during the COVID-19 pandemic. It found that motor symptoms progressed more quickly during the first 15 months of the pandemic than during the 15 months before it. Some background PD symptoms involving muscles and...
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In a nutshell This study looked at the effect of safinamide (Xadago) on rapid eye movement (REM) sleep behavioral disorder (RBD) in patients with Parkinson's disease (PD). It found that safinamide 50 mg daily improved RBD symptoms in these patients. Some background Patients with PD sometimes suffer from REM sleep...
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In a nutshell This study looked at the effectiveness of deep brain stimulation (DBS) in patients with Parkinson's disease (PD) and stomach problems. It found that DBS was associated with an improvement in stomach disorders and a reduced need for medication. Some background PD is a neurologic condition that can be difficult to treat as...
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In a nutshell This study looked at the use of levodopa-carbidopa intestinal gel (LCIG; Duodopa) for the treatment of severe dyskinesia in patients with advanced Parkinson's disease (PD). It found that LCIG improved symptoms in most patients but that dose adjustments were needed throughout treatment. Some background Parkinson's...
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In a nutshell This study investigated the association between smoking cigarettes and psychosis in patients with Parkinson´s disease (PD). Researchers suggested that smoking may increase the risk of psychotic symptoms in PD patients. Some background PD is a chronic disease that affects the brain cells over time. Brain cells are responsible...
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In a nutshell This study investigated the effectiveness of a treatment program with physical therapy and music (PTM) for patients with Parkinson´s disease. Researchers suggested that PTM improved the quality of life of these patients. Some background Parkinson´s disease affects brain cells. These cells stop controlling body functions...
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In a nutshell This study reviewed the long-term effects of levodopa/carbidopa intestinal gel (LCIG; Duodopa®) in patients with Parkinson´s disease (PD) and wearing-off symptoms. This study concluded that LCIG reduced off-time and improved off-symptoms in the long-term in these patients. Some background PD is a chronic disorder that...
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In a nutshell This article studied whether carbidopa-levodopa enteral suspension (CLES; Duopa) treatment improves the quality of life of patients with Parkinson's disease (PD). The authors found that CLES improved both quality of life and the ability of patients to perform daily activities. Some background Parkinson's disease (PD) is...
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In a nutshell This study investigated the effectiveness of dance classes in the treatment of Parkinson’s disease (PD). Researchers suggested that dance classes improve the symptoms of these patients. Some background PD is a chronic disease of the brain. It affects brain cells causing symptoms such as tremors. This decreases the ability of...
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