In a nutshell This study investigated the effects of an 8-week high-intensity physical exercise on overall movement of patients with Parkinson's disease (PD). Researchers suggested that this type of exercise is associated with improved mobility in these patients. Some background PD is a chronic disorder that affects nearly 6.1 million people...
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Increasing carbidopa dose together with levodopa, and entacapone treatment improves the outcomes in Parkinson’s disease
In a nutshell This study investigated whether increasing the doses of carbidopa/levodopa treatment improves the outcomes of patients with Parkinson's disease. Researchers suggested that higher doses of carbidopa together with levodopa and entacapone should be considered as an option for the treatment of patients with Parkinson's disease. Some...
Read MoreBright light therapy improves the quality of sleep of patients with Parkinson disease
In a nutshell This study investigated the effectiveness of bright light therapy (BLT) in treating depression and sleep quality in patients with Parkinson's disease. Researchers suggested that BLT helps in reducing depressive symptoms and improving the quality of sleep in these patients. Some background Patients with Parkinson's disease may...
Read MoreDeep brain stimulation improves tremors in patients with Parkinson disease
In a nutshell This study compared the effectiveness of deep brain stimulation (DBS) in 2 regions of the brain, subthalamic (SN) and globus pallidus interna (GPI) to treat tremors in patients with Parkinson's disease (PD). Researchers suggested that both treatments improved tremors equally in these patients. Some background PD is a...
Read MoreLevodopa oral inhalation powder CVT-301 improves symptoms in patients with Parkinson disease
In a nutshell This study investigated the effectiveness and safety of CVT-301 (levodopa oral inhalation powder; Inbrija) for the treatment of patients with Parkinson's disease (PD). Researchers suggested that CVT-301 can improve the symptoms of patients with PD with manageable side effects. Some background The standard treatment for PD is...
Read MoreUpdate on treatments for nonmotor symptoms of Parkinson’s disease
In a nutshell This study aimed to review the advanced treatment options available for non-motor symptoms of Parkinson's disease (PD). Some background Parkinson’s disease (PD) affects the nerve cells in the brain that produce dopamine. PD symptoms include muscle rigidity, tremors, and changes in speech and walk. Symptoms can be...
Read MoreSubthalamic deep brain stimulation improves posture in patients with Parkinson’s disease
In a nutshell This study investigated the effect of subthalamic deep brain stimulation (SDBS) in patients with Parkinson's disease and abnormal body position (posture). Researchers suggested that SDBS has an effect on these patients increasing the effect of medication alone. Some background In advanced Parkinson disease, abnormal trunk and neck...
Read MoreAdvanced treatment options for Parkinson’s disease
In a nutshell This study aimed to investigate the advanced treatment options available to treat Parkinson's disease. This study found that advanced treatment options should be used to create an individual treatment option for each patient to help with motor and non-motor symptoms. Some background Parkinson’s disease (PD) affects...
Read MoreBeyond Medication for Parkinson’s Disease: Focused Ultrasound
Around one million people in the US have Parkinson’s disease. In Parkinson’s, the dopamine-producing cells of the brain–in an area called the substantia nigra–die off. All neurodegenerative diseases have deposits of abnormal proteins, in fact, neurobiologists call them “protein-opathies,” Paul Fishman, MD PhD professor of...
Read MoreThe impact of lifestyle factors on Parkinson’s disease
In a nutshell This study aimed to investigate the effect of lifestyle factors (LFs) on Parkinson's disease (PD). This study found that LFs can influence PD progression and mortality. Some background Parkinson’s disease (PD) affects the nerve cells in the brain that produce a substance called dopamine. This results in symptoms...
Read MoreLevodopa in the treatment of Parkinson’s disease: when to start treatment?
In a nutshell This study investigated if levodopa has an effect on Parkinson's disease (PD) progression or just treats the symptoms. Researchers suggested that treatment with levodopa improves the symptoms of these patients, without having an effect on disease progression. Some background The standard treatment for PD is levodopa. Doctors may...
Read MoreLesion surgery versus deep brain stimulation in patients with tremor
In a nutshell This study compared the use of deep brain stimulation (DBS) and lesion surgery (LS) in the treatment of tremor. This study found that LS and DBS were equally effective in these patients. Some background Tremor is an involuntary movement of a body part. It is commonly a symptom in Parkinson's disease (PD). It can also be...
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