In a nutshell This study investigated the outcomes for adolescents and young adults with diffuse large B-cell lymphoma (DLBCL). This study concluded that outcomes for these patients were comparable to those in adults older than age 40 with DLBCL. Some background DLBCL is the most common subtype of non-Hodgkin’s lymphoma (NHL) across all...
Read MoreIn a nutshell This study aimed to investigate if enalapril influences anthracycline-induced cardiotoxicity in children with leukemia and lymphoma. This study concluded that enalapril has a role in reducing anthracycline-induced cardiotoxicity in these patients. Some background Anthracyclines are a class of chemotherapy drugs that can be used for...
Read MoreIn a nutshell This study is evaluating the safety and effectiveness of a new drug called lisocabtagene maraleucel compared to standard chemotherapy for relapsed (recurrent) or refractory (does not respond to treatment) non-Hodgkin’s lymphoma (NHL). The main outcome to be measured will be time to any disease-related complication. The...
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In a nutshell This study evaluated the outcomes of patients with localized (cancer has not spread to other parts of the body) early-stage follicular lymphoma (FL) after positron emission tomography/computed tomography (PET/CT) scanning. This study concluded that radiotherapy is a highly effective treatment for these patients. Some background FL is one...
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In a nutshell This study evaluated the risk of developing congestive heart failure (CHF; the muscle of the heart becomes weak and does not pump blood efficiently) in patients with non-Hodgkin’s lymphoma (NHL) after first-line chemoimmunotherapy. This study concluded that treatment containing anthracyclines was associated with a significantly higher...
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In a nutshell This study examined the effectiveness of vibration therapy on patients receiving chemotherapy for leukemia and lymphoma. Researchers found that vibration therapy improved daily function in these patients. Some background Exercise is proven to be effective in improving outcomes of patients with cancer. Chemotherapy treatment can make...
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In a nutshell This study evaluated the long-term outcomes of R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone) treatment for previously untreated patients with advanced follicular lymphoma (FL). This study concluded that R-CHOP is effective in patients with newly diagnosed advanced FL. Some background FL is the second most...
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In a nutshell This article reviewed the role of radiation therapy (RT) in the treatment of lymphoblastic lymphoma (LL). Some background LL is a rare type of non-Hodgkin’s lymphoma. This type of lymphoma develops when white blood cells, called lymphocytes, become abnormal and grow in an uncontrolled way. 90% of patients with LL have large...
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In a nutshell This study evaluated the value of PET (positron emission tomography) scanning after first-line (primary) chemoimmunotherapy in patients with previously untreated follicular lymphoma (FL). This study concluded that PET scanning is a better imaging technique than CT (computed tomography) for assessing treatment response in these...
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In a nutshell This study evaluated the effectiveness and safety of first-line (primary) treatment with VR-CAP (bortezomib, rituximab, cyclophosphamide, doxorubicin, prednisone) versus R-CHOP (VR-CAP with vincristine instead of bortezomib) alone in previously untreated patients with mantle cell lymphoma (MCL). This study concluded that VR-CAP was...
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In a nutshell This study evaluated the effectiveness of maintenance therapy with rituximab (Rituxan) in elderly patients with newly diagnosed follicular lymphoma (FL). This study concluded that maintenance rituximab treatment improved survival outcomes in these patients in a real-world setting. Some background Chemoimmunotherapy containing rituximab...
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In a nutshell This article reviewed current treatment options for patients with relapsed (cancer recurrence) or refractory (does not respond to treatment) diffuse large B-cell lymphoma (DLBCL). Some background DLBCL is one of the most common types of non-Hodgkin’s lymphoma. Typical first-line (primary) treatment involves chemoimmunotherapy....
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