In a nutshell The authors analyzed the effectiveness of ipilimumab (Yervoy) combined with fotemustine (Muphoran) in advanced melanoma patients. Some background In advanced melanoma (stage III/IV), cancer spreads rapidly from the skin to other parts of the body. This is known as...
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One out of 10 people will be diagnosed with melanoma over their lifetime. While this used to be a death sentence of only months, research has made great strides over the last decade, extending life and hope by years. Dr. Sapna Patel, assistant professor in the Department of Melanoma Medical Oncology at the University of Texas MD Anderson...
Read MoreIn a nutshell The authors analyzed the occurrence, management and risk factors of hypophysitis (a complication of the immune system following ipilimumab [Yervoy] therapy) in advanced melanoma patients. Some background In advanced melanoma (stage III/IV), cancer spreads rapidly from the skin to other parts of the body....
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In a nutshell The authors analyzed the effect of sentinel lymph node biopsy (SLNB – a surgical procedure) on the circulatory system of skin melanoma patients. Some background In primary cutaneous malignant melanoma (PCMM) the cancer tends to spread from the skin to other parts of the body. Sentinel lymph node (SLN) is the...
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A cancer diagnosis is overwhelming. So is the prospect of telling your children about a cancer diagnosis. Social media makes it possible for parents to share strategies and provide guidance to others facing this challenge. Here are some insights. Insight 1: Tell Your Children the News Parents protect. The natural inclination is to keep diagnoses of...
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In a nutshell The authors evaluated the factors responsible for long-term survival in advanced melanoma. Some background In advanced melanoma (stage III/IV) cancer spreads from the skin to other parts of the body (metastasis). Less than 2% of advanced melanoma patients survive longer than 5 years following treatment. The median (midpoint)...
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In a nutshell The authors analyzed the adverse effect of combination treatment with radiation and targeted therapy in melanoma. Some background In advanced melanoma (stage III/IV), cancer spreads from the skin to other parts of the body. In the majority of advanced melanoma patients, BRAF genes are mutated...
Read MoreIn a nutshell The authors analyzed the 5-year survival rate in advanced melanoma patients treated with a combination of ipilimumab (Yervoy) and dacarbazine (DTIC, DTIC-Dome) in a phase III clinical trial. Some background In advanced melanoma (stage III/IV), cancer spreads from the skin to other parts of the...
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“Love and compassion are necessities, not luxuries. Without them humanity cannot survive.” ~Dalai Lama In 2008, Audrey Guth, mother and president of Diamond Personnel, a nanny placement agency in Toronto Canada, arrived at the hospital for breast cancer chemotherapy. She saw mothers receiving chemotherapy infusions holding “really young...
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In a nutshell The authors evaluated the effect of dabrafenib (Tafinlar) in disease progression in melanoma patients with cancer that has spread to the brain (metastasis). Some background In advanced melanoma (stage III/IV) cancer spreads from the skin to other parts of the body, most commonly, to the brain. In...
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In a nutshell The authors evaluated the effectiveness of combination therapy in advanced melanoma patients with mutated (permanent changes) BRAF genes. Some background In advanced melanoma (stage III/ IV), cancer spreads from the skin to other parts of the body. Targeted therapy has been shown to improve patient outcomes in the advanced...
Read MoreIn a nutshell The authors reviewed different immunotherapies for advanced melanoma. Some background In advanced melanoma (stage III/IV), cancer spreads from the skin to other parts of the body. Immunotherapy is a common treatment used in advanced melanoma. It uses the body’s own immune system to fight cancer. This...
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