In a nutshell The authors analyzed the patterns of relapse in patients with head and neck melanoma treated with surgery and radiation therapy. Some background Skin melanoma of head and neck is often associated with poor survival. Surgical removal of the affected lymph nodes (tiny, bean-shaped organ that help fight infection) along with the...
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In a nutshell The authors analyzed the effectiveness of continued treatment with dabrafenib (Tafinlar) and vemurafenib (Zelboraf) in advanced melanoma after disease progression despite treatment with these drugs. Some background In advanced melanoma (stage 3/4), cancer spreads from the skin to other parts of the body. BRAF genes are...
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In a nutshell The authors assessed the risk of eye inflammation in late-stage melanoma patients treated with vemurafenib (Zelboraf). Some background In advanced melanoma (stage 3/4), cancer spreads from the skin to other parts of the body. BRAF genes are often mutated (permanently changed) in advanced melanoma. BRAF inhibitors (BRAFi) such as...
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Dr. Michael Wong from the University of Southern California, Norris Comprehensive Cancer Center considers the correlation between patients’ responses to treatment and the eventuality of stopping treatment. Dr. Wong argues disease and treatment differ from patient to patient. Tune in to learn more. Transcript Donna: I’m Donna...
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In a nutshell The authors examined the cellular environment in melanoma samples and its effect on outcome of patients. Some background In skin melanoma, the sentinel lymph node (SLN) is the first lymph node (tiny, bean-shaped organ that helps fight infection) to which the cancer cells are believed to spread (micrometastasis). The presence of...
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Recorded on June 1, 2015 Sapna Patel, MD, Assistant Professor, Department of Melanoma Medical Oncology The University of Texas MD Anderson Cancer Center Carol Preston: We talk about targeted therapies, immunotherapies. I'm also wondering about patient access to these therapies. I know it's been a hot topic at ASCO...
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In a nutshell The authors determined the factors that predict response to melphalan (Alkeran) delivered through isolated limb infusion (a technique to apply drugs at the tumor sites in melanoma). Some background Melanoma is sensitive to chemotherapy drugs, resulting in higher occurrences of adverse events. But the disease requires higher dose...
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In a nutshell The authors reviewed different treatment options available for melanoma patients with cancer spread to the liver. Some background In advanced melanoma (stages 3 and 4), cancer has spreads from the skin to other parts of the body. This is known as metastasis. Treatment of liver metastasis in advanced melanoma still remains a...
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In a nutshell The authors analyzed the effect of combination treatment with inerleukin-2 (Proleukin) injected in skin, with imiquimod (Zyclara) ointment in advanced skin cancer. Some background In advanced skin melanoma (stage III/IV), cancer spreads rapidly from the skin to the surrounding lymph nodes and the lymphatic channels (important part of...
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In a nutshell This phase 1 clinical trial recruiting in Buffalo, New York aims to evaluate the side effects and best dose of a vaccine therapy for patients with advanced (stage III/IV) melanoma that has spread from the skin to other parts of the body. The primary outcome to be investigated is the maximum tolerated dose (MTD) and treatment-related...
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Latest Technology Analyzes Disease Progression from Patient Power on Vimeo. Recorded on March 28, 2015 Mark Gimbel, MD Surgical Oncologist Banner MD Anderson Cancer Center Michael Wong, MD, PhD Head – Solid Tumors Section, Skin Cancer and Melanoma Clinics USC Norris Comprehensive Cancer Center Carol...
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In a nutshell The authors investigated the effectiveness and patient response (tolerance) to vemurafenib (Zelboraf) treatment in advanced melanoma. Some background In advanced melanoma (stage III/ IV), cancer spreads from the skin to other parts of the body (metastasis). BRAF genes are often mutated (permanently...
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