In a nutshell The authors aimed to analyze the effect of different surgical procedures on survival of stage I non-small cell lung cancer (NSCLC) patients. Some background NSCLC is the most common type of lung cancer. In stage I (early stage) NSCLC, surgery is the treatment of choice. There are three main surgical procedures that could be performed...
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In a nutshell In this review, the authors summarized different treatment strategies based on clinical trial findings in epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) patients. Some background NSCLC is the most common type of lung cancer. In advanced NSCLC patients, the EGFR gene (produces proteins involved...
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“I also know that the sooner I die, the more money my family will have.” ~from the post Why Advocate? by Lori Marx-Rubiner On hearing the word “cancer” from your physician, your first thoughts are naturally on treatment. In fact, your focus should be on treatment. Unfortunately and sometimes tragically, in the US finances need to be a top...
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In a nutshell This study aimed to assess use of dacomitinib in patients with advanced non-small cell lung cancer (NSCLC) who had previously failed to respond to chemotherapy and erlotinib (Tarceva). Some background NSCLC is the most common type of lung cancer. Erlotinib and gefitinib (Iressa) are used to treat NSCLC. They...
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In a nutshell This study investigated whether the levels of certain cancer markers (CEC and soluble CD146) could predict the outcome for patients with non small cell lung cancer (NSCLC) undergoing surgery. Some background Markers for a disease are generally proteins which are detected at high levels in one group of patients. These markers can be...
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In a nutshell The authors aimed to determine the psychological effect of advanced lung cancer on patients and their family caregivers. Some background Patients with advanced lung cancer experience higher levels of emotional and physical distress compared to patients with other cancers, which can effect their own suffering as well as their...
Read MoreIn a nutshell The authors aimed to determine the effect of cytokine-induced killer cells for treatment of non-small cell lung cancer. Some background Cytokine-induced killer cells (CIK) are man-made immune cells (fight infection and disease) that can recognize infected or cancerous cells in the absence of other immune cells, which allows for...
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In a nutshell This study examined whether a home-based walking exercise program was effective in reducing anxiety, depression and cancer-related symptoms in lung cancer patients. Some background Approximately 34% of lung cancer patients experience anxiety and approximately 33% experience depression. Lung cancer patients also experience...
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In a nutshell The authors aimed to determine how microscopic vessel invasion affects lung cancer patient outcome. Some background The visceral pleura are the membranes surrounding the lungs. In lung cancer, the presence of tumors in the visceral pleura (known as visceral pleural invasion – VPI), is a factor used in standard...
Read MoreIn a nutshell This study compared the long-term outcome for non-small cell lung cancer patients who underwent video-assisted surgery and those who underwent open lung surgery. Some background Video-assisted thoracoscopic surgery (VATS) involves making cuts in the chest wall and placing a scope specifically designed to view the lungs through...
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In a nutshell The authors aimed to determine the effects of dalotuzumab in treating small-cell lung cancer when combined with cisplatin and etoposide. Some background Extensive-stage small-cell lung cancer (SCLC – cancer has spread outside of the chest) represents 15% of all lung cancer cases. Though numerous treatments have been used over...
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In a nutshell The authors aimed to determine whether levels of YAP protein could predict the success of treatment in patients with lung cancer. Some background YAP protein is a protein active in many cancers that can have a positive or negative effect depending on the location. When YAP protein is present in the nucleus (brain of the cancer...
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