In a nutshell This study wanted to find which combination of medications worked best for advanced non-small cell lung cancer, nab-paclitaxel (Abraxane) alone, or nab-paclitaxel plus CC-486. The study found that there was no benefit seen when CC-486 was added to treatment with nab-paclitaxel. Some background There are a number of options for...
Read MoreIn a nutshell This paper is about how to diagnose, treat, and follow up on non-small cell lung cancer cases that have spread through the body. The paper overall noted that non-small cell lung cancer which has spread is often very aggressive and hard to treat, and that methods of treatment are still being developed. Some background Non-small...
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In a nutshell This study wanted to find out if using the medication erlotinib (Tarceva) in patients with non-small cell lung cancer improved survival. The study found that using erlotinib was safe, and may reduce the need for radical surgery in patients with non-small cell lung cancer. Some background Epidermal growth factor receptor (EGFR) is...
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In a nutshell This study wanted to find out which type of medication is better for patients with lung cancer and cancer of the head and neck, cisplatin (Platinol) or lipoplatin (Nanoplatin). The study found that lipoplatin was better overall, and had less side effects than cisplatin. Some background Cisplatin has been used as a type of chemotherapy...
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In a nutshell This study wanted to find out how the timing of radiation therapy affected survival in patients with lung cancer who underwent surgery. The study found that there was no difference in survival based on timing of radiation therapy. Some background There are a number of options for treatment of non-small cell lung cancer. Surgery...
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In a nutshell This trial is looking to compare the effectiveness of local therapy (surgery or radiotherapy) plus ipilimumab (Yervoy) and nivolumab (Opdivo) to ipilimumab and nivolumab alone in patients with metastatic (has spread) non-small cell lung cancer (NSCLC). The main outcome that will be measured is overall...
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In a nutshell This study wanted to find out if adding extra treatment targeted to the liver alongside treatment with EGFR inhibitors helped in patients with lung cancer that had spread to the liver. The study found that adding the extra treatment meant the patients survived longer compared to treatment with EGFR inhibitors alone. Some background...
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In a nutshell This study wanted to find out what works better in patients with lung cancer that has spread to the brain; performing radiotherapy and treatment with EGFR inhibitors one after the other, or performing radiotherapy and treatment with EGFR inhibitors at the same time. The study found that performing them at the same time had the best results....
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In a nutshell This article investigated the safety and effectiveness of durvalumab (Imfinzi) for the treatment of unresectable non-small-cell lung cancer (NSCLC). The authors concluded that durvalumab is safe and can improve survival of these patients. Some background Non-small cell lung cancer (NSCLC) is the most common kind of lung cancer....
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In a nutshell This study wanted to see how using radiotherapy on the brain impacts patients who have surgery for lung cancer. The study found that by using radiotherapy on the brain, the patients survived longer, and were less likely to have the cancer spread to their brain. Some background Small cell lung cancer is a type of lung cancer that responds...
Read MoreIn a nutshell This study wanted to find out if having a high number of a particular white blood cell before surgery was related to a worse outcome in patients with lung cancer. The study found that having a high number of white blood cells before surgery was related to a worse outcome after surgery. Some background White blood cells are the cells of...
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In a nutshell This study wanted to analyse which type of medication is best in treating lung cancer that may have spread to the brain. The study found that using erlotinib (Tarceva) is better than using gefitinib (Iressa) in preventing and treating tumors in the brain that have spread from the lung. Some background Epidermal growth factor receptor...
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