You’ve just had an x-ray and are discussing the results with your doctor. The air in the office fills with complicated words after you hear “lung cancer” from your physician. You don’t hear anything else. Not hearing or understanding anything else is part of the shock and a normal reaction. But when you can think or when you have...
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In a nutshell This study compared the effectiveness and safety of chemotherapy-based combination therapies for the treatment of patients with advanced non-small cell lung cancer (NSCLC) with negative PD-L1 expression. The data showed that pembrolizumab (Keytruda) plus chemotherapy combination was the best treatment regimen for improving overall survival...
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In a nutshell This study investigated the effect of thoracic tumor radiotherapy on overall survival (OS) in patients with metastatic non-small-cell lung cancer (NSCLC) with malignant pleural effusion (MPE). The authors concluded that thoracic tumor radiotherapy effectively improved OS with acceptable toxicity levels in these patients. Some background...
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In a nutshell This study evaluated the effectiveness and safety of prophylactic cranial irradiation (PCI) in patients with extensive stage (ES) small cell lung cancer (SCLC). The data indicated that PCI may decrease the occurrence of brain metastases in patients with ES-SCLC and improve 1-year survival time, without improving the overall survival...
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In a nutshell This evaluated the long-term outcomes of nivolumab (Opdivo) plus ipilimumab (Yervoy) versus chemotherapy as first-line treatment for advanced non-small cell lung cancer (NSCLC). The data showed that nivolumab plus ipilimumab increased the long-term overall survival versus chemotherapy in these patients. Some background NSCLC is the most...
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In a nutshell This study investigated the effectiveness and safety outcomes of toripalimab (Tuoyi) in combination with chemotherapy as a first-line treatment in patients with advanced non-small cell lung cancer (NSCLC). The data showed that toripalimab in combination with chemotherapy significantly improved overall survival and survival without cancer...
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In a nutshell This study evaluated the risk of cardiovascular (CV; heart and blood vessels) side effects in cancer patients treated with PD-1/PD-L1 inhibitors. The data showed that PD-1/PD-L1 inhibitors alone or combined with chemotherapy significantly increased the risk of CV side effects. PD-1/PD-L1 inhibitors combined with chemotherapy significantly...
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In a nutshell This study evaluated the effectiveness and safety outcomes of atezolizumab (Tecentriq) given before surgery for the treatment of patients with non-small cell lung cancer (NSCLC). The data showed that atezolizumab given before surgery was safe and effective for patients with NSCLC. Some background Non-small cell lung cancer (NSCLC)...
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In a nutshell This study evaluated the effectiveness and safety outcomes of cemiplimab (Libtayo) plus chemotherapy as first-line treatment in patients with advanced non-small cell lung cancer (NSCLC). The data showed that cemiplimab plus chemotherapy as first-line treatment was effective with manageable side effects in these patients. Some...
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In a nutshell This study compared the effectiveness and safety between immune checkpoint inhibitors (ICIs) and docetaxel (Taxotere) therapy alone in patients with non-small cell lung cancer (NSCLC). The data showed ICIs significantly improved the survival outcomes with fewer serious side effects compared to docetaxel alone for the treatment of patients...
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In a nutshell This study evaluated the effectiveness and safety of different platinum-based chemotherapy regimens given after surgery for the treatment of early-stage resected non-small cell lung cancer (NSCLC). The authors concluded that the combination of cisplatin (Platinol)-vinorelbine (Nevelbine) improved the outcomes of these patients. Also, the...
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In a nutshell This study evaluated the effectiveness and safety of anlotinib (AL3818) as a third-line treatment in patients with advanced non-small cell lung cancer (NSCLC). The data showed that anlotinib as a third-line treatment was effective with manageable side effects in these patients. Some background NSCLC is the most common form of lung...
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