In a nutshell This study aimed to compare two salvage chemotherapy regimens for relapsed/refractory acute myeloid leukemia. This study concluded that there were no significant differences between the two regimens apart from cost. Some background Salvage chemotherapy is used to treat cancers that do not respond to other treatments. Relapsed...
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A review of CAR-T cell therapy for CLL
In a nutshell This study reviewed CAR-T cell therapy, a new type of immunotherapy, for chronic lymphocytic leukemia (CLL). Some background Chimeric antigen receptor (CAR) T-cell therapy helps the immune system to fight cancer cells. In this treatment, immune cells (the T-cells) are removed from the blood. The T-cells are then genetically modified...
Read MoreGetting off the drugs: Tapering immunosuppressive agents after transplant in patients with advanced acute myeloid leukemia
In a nutshell This study aimed to investigate the effect of early tapering of immunosuppressive agents after stem cell transplants in patients with acute myeloid leukemia. This study concluded that early tapering of immunosuppressive agents after stem fell transplants in these patients can improve survival. Some background Allogeneic...
Read MoreCan BMI impact outcomes of children with acute leukemia who undergo a transplant?
In a nutshell This study aimed to investigate if body mass index can impact outcomes of children with acute leukemia undergoing stem cell transplantation. This study concluded that being underweight at the time of transplant is associated with an increased risk of acute graft versus host disease in these patients. Some background Body mass...
Read MoreWhat is Neutropenia?
There are 1.6 million people diagnosed with cancer in the US each year. Of these, 650,000 receive chemotherapy. Did you know that 60,000 people a year are hospitalized for neutropenia, a common side effect of chemotherapy? One in fourteen die because of it. Of the 650,000 receiving chemotherapy, 104,000 are not aware of neutropenia and 52,000 don’t...
Read MoreCardiometabolic complications in childhood acute lymphoblastic leukemia survivors
In a nutshell This study aimed to investigate the prevalence of cardiometabolic complications (such as high blood pressure or diabetes) in survivors of childhood acute lymphoblastic leukemia. This study concluded that cardiometabolic complications are more prevalent in these patients when compared to the general population. Some background...
Read MorePromising early results with venetoclax in patients previously treated with idelalisib
In a nutshell This study examined venetoclax (Venclexta) for patients with chronic lymphocytic leukemia (CLL) previously treated with idelalisib (Zydelig). Researchers reported good response rates and a low rate of side effects for venetoclax after idelalisib. Some background Targeted therapy is the standard treatment of CLL. This includes the...
Read MorePost-traumatic stress disorder can develop in patients with cancer
In a nutshell This study aimed to evaluate post-traumatic stress disorder (PTSD) in patients who have had treatment for cancer. This study found that a number of patients undergoing cancer treatment developed PTSD after treatment and recommended that supports are put in place. Some background Post-traumatic stress disorder (PTSD) is a...
Read MorePost-traumatic stress disorder can develop in patients with cancer
In a nutshell This study aimed to evaluate post-traumatic stress disorder (PTSD) in patients who have had treatment for cancer. This study found that a number of patients undergoing cancer treatment developed PTSD after treatment and recommended that supports are put in place. Some background Post-traumatic stress disorder (PTSD) is a...
Read MorePost-traumatic stress disorder can develop in patients with cancer
In a nutshell This study aimed to evaluate post-traumatic stress disorder (PTSD) in patients who have had treatment for cancer. This study found that a number of patients undergoing cancer treatment developed PTSD after treatment and recommended that supports are put in place. Some background Post-traumatic stress disorder (PTSD) is a...
Read MoreEmergencies and Illness
After three hurricanes, flooding, fires and mudslides, and now severe cold and snow in the Deep South and throughout the country, the US has had its share of emergencies. Are you prepared? For people who rely on oxygen, who are on dialysis, have diabetes or other serious conditions, it is time to think about putting together some of the essentials. What...
Read MoreCan stem cell transplants for acute leukemia have an affect on children’s motor skills?
In a nutshell This study aimed to investigate if the motor skills of pre-school children with acute leukemia were affected after treatment with hematopoietic stem cell transplant. This study concluded that treatment with hematopoietic stem cell transplant can have a negative impact on this group of patients. Some background Childhood acute...
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