In a nutshell This study looked at the risk of infections associated with ibrutinib (Imbruvica) used in the treatment of leukemia and lymphoma. Researchers found that patients receiving ibrutinib are at risk of serious infections. Some background Ibrutinib is a drug which targets certain proteins on cancer cells to stop them from working. It is often...
Read MoreIn a nutshell This study aimed to investigate the effectiveness of lenalidomide consolidation therapy after chemoimmunotherapy for patients with chronic lymphocytic leukemia. This study concluded that this regimen improves outcomes for these patients. Some background Fludarabine (Fludara) is a chemotherapy used for the treatment of chronic lymphocytic...
Read More
In a nutshell This study aimed to investigate the effectiveness of obinutuzumab and venetoclax after bendamustine treatment in patients with chronic lymphocytic leukemia (CLL). This study concluded that this sequence of treatment caused no unexpected side effects. It also concluded that the outcomes were comparable to established therapies for CLL. Some...
Read More
In a nutshell This study aimed to identify factors which better predict outcomes in Acute Myeloid Leukemia (AML). The authors concluded that serum albumin (a transport protein in the blood) was better at predicting AML outcomes and overall survival, but was unrelated to BMI. Some background Obesity can increase the risk...
Read More
In a nutshell This study identified the risks and incidence of congestive heart failure in children with acute leukemia (ALL or AML). The study found that risks of heart failure with ALL or AML included female gender and diagnosis at a younger age. Some background Congestive heart failure (CHF) is a condition in which the heart is unable to pump blood...
Read MoreIn a nutshell This study aimed to investigate the safety and effectiveness of imatinib in children and adolescents with chronic myeloid leukemia. This study concluded that first-line imatinib treatment in young patients with chronic myeloid leukemia is highly effective. Some background Imatinib (Gleevec) is a type of biological therapy called a...
Read More
In a nutshell This study looked at the current evidence for the effect of changing genes in T-cells (a type of immune cell) to target cancer cells in acute lymphoblastic leukemia (ALL). The study found that these T-cells were safe and effective in the treatment of ALL. Some background Acute Lymphoblastic Leukemia is a type of bone marrow cancer...
Read More
“Always trust your gut. Don’t leave your treatment in the hands of someone that you don’t trust or that does not seem like a team player. Yes, they are all smart—even brilliant—but read, read, read, and question them at every corner and challenge the standard of care. Exercise, healthy eating, learning the ropes of insurance, mediation/prayer...
Read More
In a nutshell The study looked at the effect of exercise on patients with acute leukemia under chemotherapy treatment. Researchers found that exercise had a key benefit in these patients. Some background Acute leukemia (AL) is a cancer of the bone marrow that can lead to a weak immune system. This reduces physical functions and quality of...
Read More
In a nutshell This study aimed to evaluate the effectiveness of nilotinib as a consolidation therapy for patients with chronic myeloid leukemia who had achieved a major response with imatinib. This study concluded that nilotinib led to safer, deeper responses in these patients. Some background Imatinib (Gleevec) is a tyrosine kinase inhibition (TKI)...
Read MoreIn a nutshell This study aimed to compare the outcomes of patients with chronic lymphocytic leukemia who received chemoimmunotherapy or ibrutinib. This study suggested that ibrutinib may have more favorable outcomes for these patients when compared to chemoimmunotherapy. Some background Chemoimmunotherapy (CIT) is a treatment option that can be used...
Read MoreIn a nutshell This study aimed to create a safe and effective low-intensity chemotherapy treatment plan for elderly patients with AML . This is an ongoing clinical trial and so far the authors have found the therapy has been safe and effective. Some background Outcomes for elderly patients with AML in the past have not been good due to the high...
Read More
