In a nutshell This study looked at the safety and effectiveness of adding lomustine (Gleostine) to chemotherapy in the treatment of acute myeloid leukemia in patients aged over 60. Researchers found that this treatment improved outcomes for elderly patients with AML. Some background Acute myeloid leukemia (AML) is a cancer of the bone marrow....
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In a nutshell This study looked at the effectiveness of adding inotuzumab ozogamicin (Besponsa) and blinatumomab (Blincyto) to low-intensity chemotherapy in the treatment of ALL. Researchers found that this combination of treatment was effective in these patients. Some background Acute lymphoblastic leukemia (ALL) is a cancer of the bone marrow. This...
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In a nutshell This study looked at the use of specific T-cells to treat acute lymphoblastic leukemia. Researchers found that using these cells was effective in the treatment of these patients. Some background Acute lymphoblastic leukemia (ALL) is a type of cancer of the bone marrow. This can lead to abnormal cells in the immune system. It is often...
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In a nutshell This study looked at the safety and effectiveness of blinatumomab (Blincyto) in the treatment of unresponsive acute lymphoblastic leukemia (ALL). Researchers found that blinatumomab was safe and effective in the treatment of these patients. Some background Acute lymphoblastic leukemia is a type of cancer of the bone marrow. This can lead...
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In a nutshell This study aimed to investigate the safety and effectiveness of a combination of lenalidomide (Revlimid), fludarabine (Fludara) and rituximab (Rituxan) in patients with previously untreated chronic lymphocytic leukemia. This study concluded that this combination was effective, but the tolerability varied between...
Read MoreIn a nutshell This study looked at the effectiveness of chemotherapy combined with imatinib (Glivec) in the treatment of acute lymphoblastic leukemia (ALL) in patients with abnormal genes. Researchers found that this treatment was effective in this group of patients. Some background Acute lymphoblastic leukemia is a type of bone marrow cancer. This...
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In a nutshell This study looked at new ways to treat adults with acute lymphoblastic leukemia (ALL). Researchers found that new treatments including drugs that target the immune system are an effective way to treat ALL in adults. Some background ALL is a cancer of the bone marrow that affects both children and adults. It is often treated with drugs...
Read MoreIn a nutshell This study aimed to investigate the symptom burden on patients with chronic phase chronic myeloid leukemia (CP-CML) who were treated with second or third generation tyrosine kinase inhibitors. This study concluded that the side effects of this treatment may affect the quality of life for these patients. Some background Chronic myeloid...
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In a nutshell This study looked at the treatment of low blood cell counts in patients with chronic lymphocytic leukemia (CLL). Researchers found that targeted therapies are effective in the treatment of this condition in CLL. Some background Chronic lymphocytic leukemia is a cancer of the bone marrow. A complication of CLL is when the body attacks its...
Read MoreIn a nutshell This study aimed to compare healthcare resource utilization and costs associated infections in patients with chronic myeloid leukemia patients receiving dasatinib and nilotinib. This study concluded that dasatinib use is associated with higher healthcare resource utilization and health care costs compared to nilotinib due to...
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In a nutshell This study reviewed the current assessment and management of patients with chronic lymphocytic leukemia (CLL). Some background Chronic lymphocytic leukemia (CLL) is a cancer of the bone marrow. This can lead to abnormal immune cells. Treatments often target specific proteins on cancer cells (targeted therapy). These may be used...
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In a nutshell This study looked at the best clinical practice guidelines in the diagnosis and treatment of chronic myeloid leukemia (CML). The study found that management of CML should be guided by patient age, medical conditions, and side effects of the chosen drug. Some background Chronic myeloid leukemia is a cancer of the bone marrow. It results...
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