In a nutshell This study looked at the effect of imatinib (Gleevec) on kidney function in patients with chronic myeloid leukemia (CML). Researchers found that a reversible decline in kidney function was linked with long-term imatinib use in these patients. Some background Imatinib is a strong drug used to treat CML. The kidney produces a hormone that...
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In a nutshell This study wanted to look at the effect of low growth hormone (GH) on the behavior and function of adults who had acute lymphoblastic leukemia (ALL) as children. Researchers concluded that therapy for ALL may cause low GH. They also suggest that behavioral function may be affected by treatment and not by low GH. Some...
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In a nutshell This study aimed to investigate if allogeneic hematopoietic stem cell transplant is an effective treatment for atypical chronic myeloid leukemia. This study concluded that this treatment is effective in these patients. Some background Atypical chronic myeloid leukemia (aCML) and chronic neutrophilic leukemia (CNL) are cancers...
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In a nutshell This study examined If venetoclax (Venclexta) with decitabine (Dacogen) or azacitidine (Vidaza) is effective in treating elderly patients with acute myeloid leukemia (AML). This study concluded that venetoclax with decitabine or azacitidine could be an effective treatment in these patients. Some background Acute...
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In 1904, a physician wrote about a patient with leukemia who went into remission when he got the flu. Though the patient was not cured, it was a ray of hope at a time when there were no treatments for leukemia. Other cases were reported throughout the years of people with Burkitt’s Lymphoma and Hodgkin’s Lymphoma going into remission when they...
Read MoreIn a nutshell This study looked at the changes in the sense of taste of children with cancer and those who received a stem cell transplant. Researchers found that taste changes in these patients were common. Some background Cancer is often treated with powerful drugs or stem cell transplant. These may have strong side effects. In children, it is...
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In a nutshell This study looked at the effect of stopping tyrosine kinase inhibitor (TKI) therapy in patients with chronic myeloid leukemia (CML). Researchers found that stopping TKI therapy was safe in these patients under certain conditions. Some background Chronic myeloid leukemia is a cancer of the immune system. It is linked with...
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In a nutshell This study wanted to assess the safety and effectiveness of nilotinib (Tasigna) in the treatment of acute lymphoblastic leukemia (ALL) with abnormal genes. Researchers found that nilotinib was safe and effective in these patients when combined with chemotherapy. Some background Acute lymphoblastic leukemia (ALL) is a cancer of the immune...
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In a nutshell This study wanted to assess the effectiveness of using azacitidine (Vidaza) after chemotherapy to maintain response to treatment in patients with acute myeloid leukemia. Researchers found that azacitidine improves survival without disease in these patients. Some background Acute myeloid leukemia (AML) is a cancer of the immune...
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In a nutshell This study examined the safety and effectiveness of rituximab (Rituxan) to treat relapsed or unresponsive chronic lymphocytic leukemia (CLL) in a real-world setting. Authors concluded that rituximab was safe and effective in these patients. Some background Chronic lymphocytic leukemia is a cancer of the immune system. It...
Read MoreIn a nutshell This study aimed to investigate patient well-being and patient-reported outcomes in previously treated patients with chronic lymphocytic leukemia who receive ibrutinib (Imbruvica) or ofatumumab (Arzerra). They concluded that ibrutinib can improve quality of life while prolonging survival in these patients. Some background...
Read MoreIn a nutshell This trial is looking at the effectiveness of zanubrutinib compared to ibrutinib in the treatment of patients with unresponsive or relapsed chronic lymphocytic leukemia (CLL). The main outcome to be measured will be overall response rate. The study will be carried out in the United States. The details Chronic...
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