In a nutshell This study aimed to investigate the occurrence of second cancers in patients with chronic myeloid leukemia (CML). This study concluded that the occurrence of overall second cancers in these patients is slightly higher than that of the general population. Some background Tyrosine kinase inhibitors (TKIs) are commonly used for the...
Read MoreLeukemia Posts on Medivizor
Allogenic hematopoietic stem cell transplant for patients with unresponsive acute myeloid leukemia
In a nutshell This study aimed to investigate the effectiveness of allogeneic hemopoietic stem cell transplant (alloHSCT) in patients with unresponsive acute myeloid leukemia. This study concluded that alloHSCT is the best treatment option for these patients. Some background Patients with unresponsive acute myeloid leukemia (AML) are those...
Read MoreA long term follow-up study of young people with acute lymphoblastic leukemia.
In a nutshell This study examined the long-term effectiveness of different treatment strategies for acute lymphoblastic leukemia (ALL) in young people. This study concluded that augmented treatment for rapid early responders was most beneficial, with improved survival at 10 years. Some background ALL is a cancer of the bone marrow. It leads to...
Read MoreCould hyperbaric oxygen therapy improve umbilical cord blood transplantation outcomes?
In a nutshell This study examined if hyperbaric oxygen therapy is safe and can improve outcomes in umbilical cord blood transplantation. This study concluded that the use of hyperbaric oxygen therapy before umbilical cord blood transplantation is safe and can improve outcomes in certain patients. Some background Stem cells allow the production...
Read MoreLooking for elderly patients with chronic lymphocytic leukemia to test a treatment combination
In a nutshell This trial is examining the effectiveness of ibrutinib and obinutuzumab with or without venetoclax in the treatment of older patients with chronic lymphocytic leukemia (CLL). The main outcome to be measured will be survival without cancer worsening. This trial is recruiting in the United States. The details Patients with CLL are often...
Read MoreInfections after treatment in children with acute leukemia
In a nutshell This study aimed to investigate the occurrence of infections in children with acute lymphoblastic leukemia or acute myeloid leukemia patients that have completed treatment. This study concluded that infections are a common complication after treatment of these patients. Some background Acute lymphoblastic leukemia (ALL) and acute myeloid...
Read MoreLong-term effectiveness of tyrosine kinase inhibitors for newly diagnosed chronic-phase chronic myeloid leukemia
In a nutshell This study aimed to investigate the long-term safety and effectiveness of tyrosine kinase inhibitors for chronic-phase chronic myeloid leukemia. This study concluded that the outcomes for these patients are satisfactory and reliable. Some background Patients with chronic phase chronic myeloid leukemia (CP-CML) generally have mild...
Read MoreSearching for patients to try a new therapy for non-responsive leukemia/lymphoma after stem-cell transplant.
In a nutshell This study will investigate the effects of ibrutinib (Imbruvica) in patients with non-responsive leukemia/lymphoma after a stem-cell transplant. The main outcome that will be measured is the time after treatment before patients experience cancer worsening. This trial is recruiting in the United States. The details Some patients with...
Read MoreSearching for patients with newly-diagnosed AML to try this new treatment option
In a nutshell This Phase 3 study is evaluating the safety and effectiveness of midostaurin (Rydapt) combined with chemotherapy for patients with newly-diagnosed acute myeloid leukemia (AML). The main outcome to be measured will be event-free survival at 5 years. The details Previous studies have shown that midostaurin combined with chemotherapy is...
Read MoreIs entospletinib an effective treatment for relapsed or unresponsive chronic lymphocytic leukemia?
In a nutshell This study examined if entospletinib can be used as a treatment for relapsed or unresponsive chronic lymphocytic leukemia (CLL). This study concluded entospletinib has disease reducing activity in patients with CLL, where previous treatment has failed. Some background Chronic lymphocytic leukemia (CLL) is a cancer of the bone marrow. It...
Read MoreSearching for patients to test a combination of targeted therapies for chronic lymphocytic leukemia
In a nutshell This trial is examining the effectiveness of ibrutinib (Imbruvica) and obinutuzumab (Gazyva) with or without venetoclax (Venclexta) in the treatment of chronic lymphocytic leukemia (CLL). The main outcome to be measured will be survival without cancer growing or spreading. This trial is recruiting in various places around the...
Read MoreStem cell transplant for blood cancers: mother vs unrelated donors
In a nutshell This study compared the effectiveness of stem cell transplant from a mother donor compared to an unrelated donor in the treatment of cancers of the blood. Researchers found that mother donors could have some better outcomes but with an increased risk of a reaction to the transplant. Some background Cancers of the blood often involve the...
Read More
