In a nutshell This study aimed to investigate outcomes for patients with chronic-phase chronic myeloid leukemia who received nilotinib as a first-line treatment. This study concluded that nilotinib is a valuable treatment option for these patients. Some background Nilotinib (Tasigna) is a targeted therapy...
Read More
In a nutshell This study aimed to investigate treatment response and outcome for patients of 75 years and older with chronic myeloid leukemia treated with imatinib (Gleevec). This study concluded that imatinib is important in the frontline treatment of these patients. Some background...
Read More
In a nutshell This study aimed to investigate the outcomes of stem cell transplant in patients with blast crisis chronic myeloid leukemia who were pre-treated with tyrosine kinase inhibitors. This study concluded that the survival of these patients was strongly dependent on pretransplant remission status. Some background...
Read More
In a nutshell This study aimed to investigate the frequency of BCR-ABL kinase domain mutation detection and its prognostic significance in patients with chronic-phase chronic myeloid leukemia (CP-CML) treated with tyrosine kinase inhibitors (TKIs). This study concluded that early mutation detection and use of 2nd and...
Read More
In a nutshell This study aimed to investigate if a modified Berlin-Frankfurt-Münster (BFM) regimen would be a safe and effective method of treatment for adult patients with newly diagnosed acute lymphoblastic leukemia (ALL). This study concluded that this regimen is well tolerated and effective...
Read More
In a nutshell This study aimed to investigate the impact of donor type for stem cell transplant in pediatric acute lymphoblastic leukemia patients. This study concluded that the outcomes of transplants from matched donor and HLA-identical sibling donors are similar. Some background...
Read MoreIn a nutshell This study aimed to investigate the relationship between immunoglobulin (Ig) levels and clinical outcomes in patients with chronic lymphocytic leukemia. This study concluded that levels of IgG and IgA at diagnosis are important prognostic markers for infection in these patients. Some background Immunoglobulins (Ig)...
Read More
In a nutshell This study aimed to investigate if stem cell transplantation (SCT) could improve the long-term prognosis of minimal residual disease negative complete remission (MRD-CR) patients with acute lymphocytic leukemia (ALL) after chimeric antigen receptor-modified (CAR) T-cell therapy. This study concluded that this...
Read MoreIn a nutshell This study aimed to compare the outcomes for patients with chronic lymphocytic leukemia who achieved detectable and undetectable minimal residual disease (MRD). This study concluded that patients with undetectable MRD had better outcomes than those with detectable MRD. Some background Minimal...
Read MoreIn a nutshell This study aimed to investigate if venetoclax would enable patients with acute myeloid leukemia to overcome disease progression after hypomethylating agents. This study concluded that adding venetoclax to these patient's treatment may result in a substantial...
Read MoreIn a nutshell This study aimed to investigate the impact of testosterone levels before a stem cell transplantation (SCT) on outcomes in male patients with acute myeloid leukemia (AML). This study concluded that testosterone levels may predict the outcomes of these patients. Some background Testosterone is a male...
Read MoreIn a nutshell This study aimed to investigate the long-term safety of ibrutinib as a single-agent treatment for patients with chronic lymphocytic leukemia. This study concluded that side effects were mainly grade 1 or 2 and were manageable during prolonged ibrutinib treatment in these patients. Some background...
Read More
