In a nutshell This study aimed to investigate the combination of low-dose decitabine, medium-dose cytarabine and umbilical cord blood infusion as a consolidation therapy for elderly patients with acute myeloid leukemia. This study concluded that this treatment combination was effective in these patients. Some...
Read MoreIn a nutshell This study aimed to investigate if treatment with inotuzumab ozogamicin in patients with relapsed/unresponsive acute lymphoblastic leukemia was associated with lower healthcare system burden compared to standard of care. This study...
Read MoreIn a nutshell This study investigated if there is a higher risk of cardiovascular disease (CVD) in cancer survivors. They found that cancer survivors have a higher risk of CVD. Some background Improved cancer detection and treatment has increased the rates of survival. The number of cancer survivors living for more than 10 years is growing. Some...
Read More
In a nutshell This study evaluated the safety and effectiveness of total lymphoid irradiation and anti-thymocyte globulin (TLI-ATG) conditioning before stem cell transplantation (SCT) in patients with lymphoma or leukemia. This study concluded that this regimen was well-tolerated and effective, especially for patients who had multiple lines of prior...
Read More
In a nutshell This article reviewed different options to preserve or restore fertility in female patients with lymphoma or leukemia. Some background Impaired reproductive function is one possible side effect of aggressive chemotherapy and radiotherapy for cancer. In severe cases, intensive anti-cancer treatment can lead to fertility loss. 7 to 9% of...
Read More
In a nutshell This study aimed to investigate the outcomes for patients who underwent allogeneic hematopoietic stem cell transplant after treatment with blinatumomab. This study concluded that survival was driven by the response to study treatment and by salvage status regardless of transplant status. Some...
Read MoreIn a nutshell This study aimed to compare the safety and effectiveness of front-line treatments for patients with newly diagnosed chronic phase chronic myeloid leukemia. This study concluded that nilotinib, dasatinib, and radotinib are the safest and most effective treatments for these...
Read MoreIn a nutshell This study aimed to investigate the effectiveness of ibrutinib–rituximab treatment compared to standard chemoimmunotherapy in patients aged 70 or younger with previously untreated chronic lymphocytic leukemia (CLL). This study concluded that the ibrutinib–rituximab regimen provided...
Read More
In a nutshell This study aimed to investigate the safety and effectiveness of obinutuzumab in combination with fludarabine and cyclophosphamide in fit patients with chronic lymphocytic leukemia. This study concluded that this combination as frontline treatment is a promising option for these...
Read More
In a nutshell This study evaluated the safety and effectiveness of the herpes zoster vaccine (Shingrix) in patients with blood cancer who are receiving anti-cancer therapy. This study concluded that the Shingrix vaccine was effective in these patients, with manageable side effects. Some background Shingles is caused by a virus called herpes zoster....
Read More
In a nutshell This study aimed to investigate if sorafenib (Nexavar) would be a suitable maintenance agent for patients with acute myeloid leukemia who received a stem cell transplant. This study concluded that sorafenib is a safe and effective maintenance agent in these patients. Some...
Read MoreIn a nutshell This study aimed to compare the risk of infections after treatment completion for pediatric leukemia survivors and the general population. This study concluded that there was a significant association between history of leukemia therapy and increased risk of infections. Some background Infections are a common...
Read More
