In a nutshell This study aimed to investigate cancer-related cognitive (thinking and reasoning) impairment in patients with chronic lymphocytic leukemia. This study concluded that disease biology may contribute to cancer-related cognitive impairment, independent of treatment. Some background Cancer-related cognitive impairment...
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In a nutshell This study aimed to investigate treatment options for chronic lymphocytic leukemia (CLL). This study concluded that treatment results from clinical trials may not be seen in a real-life setting and that novel agents can improve outcomes for these patients. Some background Traditional treatments for CLL include...
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In a nutshell This study aimed to investigate second treatments in patients with chronic myeloid leukemia (CML) who had been initially treated with second-generation tyrosine kinase inhibitors (TKI). This study concluded that switching from second-generation TKIs in these patients was relatively uncommon. Some background...
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In a nutshell This study aimed to investigate post-transplant cyclophosphamide treatment in patients with acute myeloid leukemia. This study concluded that this treatment is safe and effective in these patients. Some background Post-transplant cyclophosphamide (PTCy) is an immune system suppressant. It can be used after...
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In a nutshell The report recommends several treatment modifications for patients with leukemia during the high-risk period of the COVID-19 pandemic. The main recommendations are to reduce clinic visits, use less intensive chemotherapy, and care through telemedicine for effective treatment. Some background Managing patients with leukemia during...
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In a nutshell This study aimed to investigate kidney function in patients with chronic-phase (CP) chronic myeloid leukemia (CML) before and after tyrosine kinase inhibitor (TKI) treatment. This study concluded that long-term TKI treatment leads to kidney side effects in these patients that may be irreversible after stopping...
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In a nutshell The study evaluated how smoking habits affect the predicted treatment outcomes in patients with acute myeloid leukemia (AML) under intense chemotherapy. The authors found that smoking status was related to poor overall survival in such patients. Some background Patient-related factors such as lifestyle choice and additional medical...
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In a nutshell This study aimed to investigate the outcomes of anti-CD19 chimeric antigen receptor T cells in patients with relapsed or refractory (unresponsive) chronic lymphocytic leukemia. This study concluded that high-dose treatment may be more effective in these patients in the long term. Some background Chimeric antigen...
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In a nutshell This study aimed to investigate the impact of maintenance treatment on cancer-related fatigue and sleep-wake rhythms in pediatric patients with acute lymphoblastic leukemia. This study concluded that sleep-wake rhythms are disturbed, physical activity levels lower and cancer-related fatigue levels higher...
Read MoreIn a nutshell The study evaluated the effects of an antioxidant-rich diet in treatment outcomes during chemotherapy in children and adolescents with acute lymphoblastic leukemia (ALL). The main finding was that the intake of antioxidant-rich food alone reduced the risk of infections during treatment in such patients. Some background Several...
Read MoreIn a nutshell The study evaluated the effectiveness and safety of combing all-trans retinoic acid (ATRA; Vesanoid), arsenic trioxide (ATO; Trisenox), and gemtuzumab ozogamicin (GO; Milotarg) in treating patients with high risk (HR) acute promyelocytic leukemia (APL). The authors found that the combination therapy was effective and well...
Read MoreIn a nutshell This study aimed to investigate the outcome of early switching from imatinib to dasatinib of patients with chronic-phase chronic myeloid leukemia with weak responses to imatinib treatment. The study concluded that this switch may offer clinical benefit in certain patients. Some background Imatinib...
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