In a nutshell This review compared medication protocols for in vitro fertilization (IVF) for women with a poor ovarian response (POR). It found that delayed start antagonist (DSA) protocol may improve IVF outcomes for patients with POR. Some background The infertility treatment IVF is a method to collect oocytes (eggs), fertilize them artificially,...
Read More
In a nutshell This study looked at how lifestyle factors before fertility treatment affect the results of in vitro fertilization (IVF). It found that moderate drinking prior to beginning IVF did not affect IVF outcomes. It also found that heavy smoking prior to IVF and high levels of exercise may reduce pregnancy rates. Some background Diet,...
Read More
In a nutshell This review compared starting ovarian stimulation (OS) for egg collection at the conventional time early in the menstrual cycle, to starting it in the luteal phase, late in the cycle. It found that both timelines led to successful egg collection. Using two collections in one cycle may improve outcomes for patients with a poor response to...
Read More
In a nutshell This study looked at using the anti-inflammatory progestin dienogest (Visanne) prior to in vitro fertilization (IVF) for patients with endometriosis with a previously failed IVF. It found that dienogest improved IVF outcomes in these women. Some background Endometriosis is a chronic illness in which cells from the lining of the uterus...
Read More
In a nutshell This review compared mild-dose ovarian stimulation (OS) for in vitro fertilization (IVF) to standard higher dose OS. It found that mild OS has fewer side effects and similar birth rates. Some background The first stage of the infertility treatment IVF is to stimulate the ovaries. The most common type of medication used is gonadotropin...
Read More
In a nutshell This review looked at how often artificial gonadotropin hormones such as human follitropin alpha (Gonal-F) caused ovarian hyperstimulation syndrome (OHSS) or blood clots. It found that these conditions are infrequent side effects of using gonadotropins to stimulate the ovaries. Some background In a natural menstrual cycle,...
Read More
In a nutshell This study investigated the best dose of follitropin delta (FD; Rekovelle) in women undergoing controlled ovarian stimulation (COS). They found that 10 micrograms of FD has similar effectiveness to the standard dose of follitropin alpha (FA; Gonal-F). Some background Assisted reproductive technology (ART)...
Read More
In a nutshell This study investigated preimplantation genetic testing for aneuploidy (PGT-A) in couples with severe male infertility. They found that PGT-A did not improve fertility outcomes in these couples. Some background Infertility affects men and women. Male factor infertility (MFI) is the cause of infertility in 30-50% of...
Read More
In a nutshell This study created a model to predict how well eggs (oocytes) develop embryos during in vitro fertilization (IVF). It found that patients with lower doses of gonadotropin (GN) hormones had better fertilization rates (FR). It also found that patients with diminished ovarian reserve (DOR) could have a high FR. Some background The...
Read More
In a nutshell This study looked at the dose of gonadotropin (GN) used for ovarian stimulation during in vitro fertilization (IVF). It found that cycles with higher GN doses may have lower birth rates. Some background The first stage of the infertility treatment IVF is to stimulate the ovaries to produce multiple follicles. This is most often done...
Read More
In a nutshell This study investigated if vitamin D (VitD) levels affect fertility outcomes after in vitro fertilization (IVF). They found that VitD levels did not seem to be associated with fertility outcomes after IVF. Some background Infertility is a common problem worldwide. Assisted reproductive technology (ART) has improved fertility...
Read More
In a nutshell This review looked at adding hyaluronic acid (HA) to the medium used to grow embryos during in vitro fertilization (IVF). It found that using HA may increase IVF birth rates. Some background The infertility treatment IVF involves fertilizing an egg and allowing it to grow it for several days in the laboratory. The embryos are...
Read More
