In a nutshell This study examined whether altering the dose and duration of clomiphene citrate (Clomid) treatment can enhance pregnancy success. Some background Clomiphene citrate (CC) is a drug used to treat infertility by inducing ovulation. It is the most commonly used drug to treat infertility as it is inexpensive, effective and safe....
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The options available to HIV patients who want children
In a nutshell This report published by the Ethics Committee of the American Society for Reproductive Medicine discusses the reproductive options available to human immunodeficiency virus (HIV)-infected patients. Some background Approximately one third of HIV-infected individuals express a desire to have children. However, these individuals also...
Read MoreBemfola: a safe and effective alternative to Gonal-f for IVF
In a nutshell This study examined whether bemfola has a similar safety and effectiveness profile as Gonal-f in women undergoing assisted reproductive technology. Some background Follicle-stimulating hormone (FSH) is a female hormone which is involved in the development of eggs in the ovaries. Gonal-f (follitropin alfa) is a drug which acts in...
Read MoreCan anti-Mullerian hormone levels predict pregnancy success?
In a nutshell This study examined the accuracy of anti-Mullerian hormone in predicting pregnancy success. Some background Tests that identify women who require fertility treatment currently measure the ovarian reserve (number of eggs remaining in the ovary). Measures of ovarian reserve such as follicle-stimulating hormone (FSH) have low accuracy....
Read MoreHow do on and off-label female infertility medications compare?
In a nutshell This article reviewed on and off-label drug use in female infertility treatment. Some background Female infertility affects millions of couples worldwide with many medications available to assist conception. Fertility treatments undergo assessment by the Food and Drug Administration (FDA) to gain a license for a particular...
Read MoreIs there a way to predict the chances of becoming pregnant after endometriosis treatment?
In a nutshell This article explored whether the Endometriosis Fertility Index is accurate at predicting the chances of conceiving after endometriosis treatment. Some background Endometriosis involves the appearance of endometrial tissue (usually found in the uterus) outside the uterus, leading to pelvic pain. It is...
Read MoreIs a poor ovarian response in IVF treatment related to microRNA levels?
In a nutshell This article explores the role of miRNA expression in women undergoing in vitro fertilization with different ovarian responses. Some background In-vitro fertilization (IVF) is when a male sperm fertilizes the females’ egg in a laboratory dish outside the body, and is implanted into the woman's uterus. It is...
Read MoreCan high progesterone levels have a negative impact on live birth rates during IVF?
In a nutshell This study examined the impact of raised progesterone levels during in vitro fertilization treatment on live birth rates. Some background Many couples experiencing infertility undergo assisted reproductive techniques such as in-vitro fertilization (IVF). In IVF, a male sperm fertilizes the females’ egg in a laboratory...
Read MoreIs MPA an oral alternative to prevent an LH surge?
In a nutshell This study examined the use of medroxyprogesterone acetate in the prevention of unwanted hormonal increase during fertility treatment. Some background In-vitro fertilization (IVF) is when a male sperm fertilizes the females’ egg in a laboratory dish outside the body, and is implanted into the woman's uterus....
Read MoreCan treatment for an ectopic pregnancy affect the chances of future IVF success?
In a nutshell This study examined the use of methotrexate or salpingectomy as a treatment for ectopic pregnancy, and explored whether these treatments affect the chances of subsequent successful in vitro fertilization cycles. Some background In-vitro fertilization (IVF) is when a male sperm fertilizes the females’ egg in a laboratory dish...
Read MoreCan IVF be successful in women with high FSH levels?
In a nutshell This study explored factors that can affect pregnancy rates in patients with a high follicle-stimulating hormone level undergoing in vitro fertilization. Some background Follicle stimulating hormone (FSH) levels are used to assess a females’ ovarian function. If FSH levels are unexpectedly high for...
Read MoreCan lifestyle alteration help patients with PCOS?
In a nutshell This article explored the abnormalities of metabolism and nutrition that occur in polycystic ovarian syndrome and the lifestyle alterations that may help. Some background Polycystic ovary syndrome (PCOS) is a hormonal problem in women where excess androgens (sex hormones such as testosterone, normally...
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