In a nutshell This study assessed whether males with normal sperm but poor sperm motility on the day of insemination had higher pregnancy rates than males with diagnosed infertility. The study concluded that even if sperm motility was low on the date of insemination, males who previously had normal sperm had better pregnancy rates. Some background...
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Does male obesity affect fertility?
In a nutshell This study evaluated current evidence of the effects of male obesity on fertility. The study concluded that male obesity is associated with reduced fertility. Some background Male infertility is the inability to reproduce naturally. It is the cause of approximately 50% of infertility cases. Defective sperm function is the most common...
Read MoreDo infections cause miscarriage?
In a nutshell This study researched the role of different infections in miscarriage. The study concluded that a number of infections were associated with miscarriage. Some background Pregnancy loss before 12 weeks is called early miscarriage. Pregnancy loss between 12 and 24 weeks is called late miscarriage. Early miscarriage occurs in one in...
Read MoreLuteinizing hormone supplements and ovarian stimulation: Timing is everything?
In a nutshell This study looked at the potential benefit of introducing luteinizing hormone (LH) earlier during ovarian stimulation in older women. Starting LH on the earlier date was shown to increase clinical pregnancy rates. Some background There is an increased number of older women (over 35) seeking help to get pregnant. Success rates usually...
Read MoreLow vitamin D levels associated with infertility
In a nutshell This study looked at vitamin D levels and pregnancy rates in patients undergoing in vitro fertilization (IVF). The study found that pregnancy rates were signficantly higher in the patients who had higher vitamin D levels. Some background Vitamin D is important for good health. The main source of vitamin D is from the action of...
Read MoreThe effects of berberine on women with polycystic ovary syndrome
In a nutshell This study assessed the effects of berberine on the menstrual cycle, ovulation rates, hormone levels and metabolism of Chinese women with polycystic ovary syndrome (PCOS). This study found that berberine may improve the menstrual pattern and ovulation rates in these patients. Some background PCOS is a syndrome in which...
Read MoreDoes PCOS increase the risk of gestational diabetes?
In a nutshell This study explored the relationship between gestational diabetes (GD) and polycystic ovarian syndrome (PCOS). This study concluded that there was a two-fold increase in the rate of GD in women who had PCOS compared to women without PCOS. Some background PCOS is a common disorder, affecting between 5% and 14% of women during their...
Read MoreCan comprehensive chromosome screening enhance IVF/ICSI success?
In a nutshell This study examined whether comprehensive chromosome screening can improve IVF/ICSI outcomes. Some background Chromosomes are structures located in each cell of the body and consist of DNA. Most cells in the human body have 23 pairs of chromosomes (46 chromosomes in total). Alterations in the number of chromosomes can...
Read MoreCould glucocorticoids help embryo implantation?
In a nutshell This study analyzed the effects of glucocorticoids given during assisted reproductive treatments. Glucocorticoids were found to increase pregnancy rates in some women, but cannot be recommended for routine use. Some background Glucocorticoids are steroid hormones with anti-inflammatory and immune suppressing effects. The use...
Read MoreThe effect of high intensity exercise on polycystic ovarian syndrome
In a nutshell This study examined whether high intensity exercise could improve the cardiometabolic profile in women with polycystic ovary syndrome. Some background Polycystic ovarian syndrome (PCOS) is associated with many hormonal and metabolic (how the body breaks down and uses energy from food) factors. In addition to having fertility problems...
Read MoreIs ulipristal acetate safe and effective for the treatment of uterine fibroids?
In a nutshell This study examined whether ulipristal acetate is safe and effective for the treatment of uterine fibroids. Some background Uterine fibroids are benign (harmless) smooth muscle tumors (myomas) that occur in the uterus. They can result in heavy menstrual bleeding, infertility and a decrease in quality of life. Patients may also...
Read MoreStimulating ovulation in unexplained infertility
In a nutshell This study examined whether letrozole can reduce the rate of multiple births without reducing the rate of pregnancy success in unexplained infertility. Some background Infertile women may undergo ovarian stimulation to stimulate the development of eggs in the ovaries. The drugs clomiphene...
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