In a nutshell This study looked at mini-incision micro-dissection testicular sperm extraction, a modified surgery to collect sperm. It found that this was a useful procedure for men who do not produce enough sperm and that it may be less invasive than other surgeries. Some background Non-obstructive azoospermia (NOA) is a condition in which a man...
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In a nutshell This study investigated if melatonin improves fertility outcomes in assisted reproduction (AR). They found that melatonin improved the clinical pregnancy rate (CPR) in AR cycles. Some background Infertility is becoming increasingly common. Assisted reproduction (AR) can be used to treat infertility. Many studies have been conducted...
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In a nutshell This study looked at the effect of stress when trying to conceive through assisted reproductive techniques. It found that stress did not impact conception rates, but that job-related stress may be associated with miscarriage. Some background Psychological stress affects the body. Stress hormones such as cortisol interact with...
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In a nutshell This study looked at the effect of an antioxidant supplement on men with infertility. It found that after taking the supplement men had improved sperm concentration, motility, and amount of DNA damage. Some background Male infertility contributes to half of all infertility cases. It is believed that oxidative stress contributes to male...
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In a nutshell This study looked at the effect of three months of coenzyme Q10 (CoQ10) on men with infertility. It found that CoQ10 supplements improved sperm parameters, oxidation levels, and amount of DNA damage. Some background Male infertility contributes to 50% of infertility cases. One cause of male infertility is reactive oxygen species (ROS)....
Read MoreIn a nutshell This study investigated the effectiveness of intracytoplasmic sperm injection (ICSI) compared to in vitro fertilization (IVF) in older women. They found that fertilization rates were similar with ICSI and in vitro fertilization (IVF) in this group of patients. Some background Assisted reproductive techniques (ART) is used to treat...
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In a nutshell This review looked at whether progesterone as vaginal supplements can reduce repeated miscarriages. It found that for women with bleeding during pregnancy and a history of miscarriage, progesterone supplements may increase the birth rate. Some background Miscarriages are a concern to women with infertility. Roughly half of miscarriages...
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In a nutshell This study compared the use of follicle-stimulating hormone (FSH) with human chorionic gonadotropin (hCG) during egg preparation for in vitro fertilization (IVF). The results showed that hCG reduced the cost of IVF considerably and was as effective as FSH for egg preparation. Some background One of the major considerations for...
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In a nutshell This review established recommendations for the treatment of unexplained infertility. Some background There is no clear cause for up to 30% of infertility cases. There are several treatment options for these couples. Expectant management uses intercourse to achieve conception. Ovarian stimulation (OS) treatment...
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In a nutshell This study looked at whether womb lining thickness and embryo quality affect the natural cycle during in vitro fertilization (NC-IVF). It found that thicker womb linings and better quality embryos were related to higher pregnancy rates. Some background IVF is an infertility treatment in which eggs (oocytes) are removed from a...
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In a nutshell This study examined if zinc and folic acid supplements for men improved sperm quality and the number of births in couples planning infertility treatment. The authors found that zinc and folic acid did not improve sperm quality or birth rates compared to a placebo. Some background In men, infertility can arise due to a number of...
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In a nutshell This study investigated factors that affect the fertility outcomes with intrauterine insemination (IUI) after controlled ovarian stimulation (COS). They found that clinical pregnancy (CPR) and live birth rates (LBR) were associated with female age. Some background Assisted reproduction (AR) is used to treat infertility. There are a...
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