In a nutshell This study investigated renin inhibitors (RI) and angiotensin-converting enzyme inhibitors (ACEI) in hypertension. They found that RI may reduce blood pressure (BP) more than ACEI, but mortality and heart attack risk was similar for both drug types. Some background Hypertension or high blood pressure (BP) is a common condition....
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Can allisartan isoproxil improve blood vessel function in patients with high blood pressure?
In a nutshell This study looked at the effects of allisartan isoproxil (Xin Li Tan) on blood vessel function in patients with hypertension (high blood pressure). They found that this medication improves blood vessel function in these patients. Some background Allisartan isoproxil (Alli) is a medication used to lower blood pressure (BP)....
Read MoreComparison of benidipine and amlodipine in the management of patients with high blood pressure and chronic kidney disease
In a nutshell This study compared two treatments for lowering blood pressure (BP) in patients with high BP and chronic kidney disease (CKD). They found that there was no difference in the BP-lowering effect between the two drugs. Some background The kidneys are responsible for filtering water out of the blood and producing urine. The...
Read MoreSearching for patients with hypertension to test a personalized management strategy
In a nutshell This trial will investigate education interventions to improve blood pressure control (BPC) in uncontrolled hypertension. The main outcome will be medication adherence (MA). This study is recruiting in California, USA. The details Hypertension is a very common condition. Blood pressure control (BPC) is important in...
Read MoreSearching for patients with treatment-resistant high-blood pressure to trial an experimental treatment.
In a nutshell This trial is aiming to assess the effectiveness and safety of a new drug (CIN-107) in patients with treatment-resistant hypertension (rHTN). The main outcome that will be measured is the change in blood pressure over a time-frame of 12-weeks. This trial is being carried out in the United States. The details Resistant...
Read MoreCan spironolactone lower blood pressure when all other drugs have failed?
In a nutshell This study looked at how effectively spironolactone (Aldactone) lowers blood pressure (BP) in patients with resistant hypertension (RH). They found that spironolactone significantly lowers BP in some patients after three months. Some background High BP can lead to strokes and heart attacks. There are many types of...
Read MoreDoes the time of day change the effect of acetylsalicylic acid on blood pressure?
In a nutshell This study investigated if the time of day alters acetylsalicylic acid (ASA; Aspirin) effects on blood pressure (BP) in patients with hypertension (high BP). They found that evening ASA had a greater reduction in BP compared to morning ASA. Some background Hypertension or high blood pressure (BP) is very common....
Read MoreWhich lifestyle change can help lower blood pressure most effectively?
In a nutshell This study investigated the effect of different kinds of lifestyle changes in patients with high blood pressure (BP) in the beginning stages (prehypertension) and full-blown hypertension. They found that a life-long change in eating called Dietary Approach to Stop Hypertension (DASH) has the most positive...
Read MoreCan vitamin D supplements help to lower blood pressure?
In a nutshell This study looked at blood pressure (BP) in patients taking high or low doses of vitamin D supplements. They found that vitamin D reduces BP in both doses and a high dose of vitamin D was more effective in reducing variations in BP. Some background High BP (hypertension) is associated with many health...
Read MoreEvaluating the effectiveness of azilsartan medoxomil in patients with essential hypertension
In a nutshell This trial was carried out to examine the effectiveness of azilsartan medoxomil (Edarbi; AZM) on lowering blood pressure (BP) in a Chinese population. The trial found that AZM was similar to valsartan (Diovan) at a 40mg-dose and more effective at a 80mg-dose. Some background One class of drugs used to...
Read MoreShould physical exercise and antihypertensive drug therapy be used for the prevention of treatment of left hear enlargement?
In a nutshell This study was carried out to examine the use of anti-high blood pressure (HBP) drug therapy with physical exercise therapy to prevent and reverse left ventricle hypertrophy (LVH; the thickening of the left side of the heart) in patients with HBP. The authors found that anti-HBP drug therapy and physical exercise should be considered...
Read MoreDoes thiazide use result in a decreased risk of heart failure in patients taking intensive blood pressure treatment?
In a nutshell This study examined whether thiazide use had a benefitted patients receiving intensive blood pressure (BP) treatment for high blood pressure (HBP) in terms of heart disease risk. The authors found that these patients had a decreased risk of having an adverse cardiovascular event. Some background Hypertension...
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