In a nutshell This phase 1 and 2 trial located in Maryland, United States aims to see whether resveratrol can have positive effects on heart and blood vessel health. The outcome to be measured is the change in stiffness of arteries. The details Resveratrol is a compound found in the skin of red grapes. Lab studies show that it may help...
Read MoreIn a nutshell This study investigated whether men and women respond differently to treatment for ischemic stroke. Some background A stroke is a disturbance of blood flow to a part of the brain. Strokes can be caused by either a ruptured blood vessel (hemorrhagic stroke), or a blood...
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In a nutshell This study investigated whether giving a combination of perindopril (at 3.5 mg) with amlodipine (2.5 mg) is effective in treating high blood pressure. Some background Hypertension (high blood pressure) refers to when pressure inside blood vessels is too high. This causes the heart to have to work harder in order to pump blood...
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In a nutshell This study investigated whether ambulatory blood pressure accurately helps predict risks of high blood pressure. Some background Hypertension (high blood pressure) occurs when pressure inside blood vessels is too high. Over time, hypertension can lead to heart-related problems such as a heart attack or stroke. A way of...
Read MoreIn a nutshell This study investigated whether reducing blood pressure too much in patients with cardiovascular disease puts them at risk of developing heart problems. Some background High blood pressure occurs when pressure inside blood vessels is too high. Cardiovascular disease refers to when arteries become narrowed due to a build up of...
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In a nutshell This study looked at whether the drug combination of amlodipine (Norvasc) and perindopril (Aceon), given at increasing doses, is successful in reducing high blood pressure. Some background Hypertension (high blood pressure) refers to when pressure inside the blood vessels is too high. This causes the heart to have to work harder...
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In a nutshell This study investigated whether drugs that reduce high blood pressure (antihypertensive drugs) reduce the risk of developing Parkinson’s disease in patients with high blood pressure. Some background High blood pressure (hypertension) is when pressure inside blood vessels is too high. This can cause a number of complications...
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In a nutshell This study investigated whether high blood pressure (hypertension) can cause the recurrence of some types of ischemic stroke. Some background Hypertension is where pressure in blood vessels is too high. This can cause blood to pool and form blood clots. The blood clots can travel to the brain and cause a stroke. A...
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In a nutshell This study investigated possible reasons why some patients with high blood pressure appear to have treatment-resistant hypertension and have uncontrolled blood pressure levels. Some background Hypertension (high blood pressure) is when pressure in blood vessels is too high. This can cause a number a health...
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In a nutshell This phase 3 trial located in the United States aims to evaluate the effectiveness of bococizumab (RN316) in reducing cardiovascular events such as a heart attack or stroke. The outcome to be examined is the occurrence of cardiovascular events. The details Bococizumab is a new drug being developed to...
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In a nutshell This study investigated whether high blood pressure determines the progression of small areas of bleeding (microbleeds) in the brain. Some background Brain microbleeds are small chronic brain hemorrhages (burst blood vessels). Brain microbleeds are associated with cognitive dysfunction (problems with mental ability such as...
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In a nutshell This trial located in United States aims to examine whether using radiation to destroy nerves of the kidney can help control hypertension (high blood pressure). The outcome to be studied is the safety and blood pressure changes. The details The kidneys play an important role in regulating blood pressure. Previous research has...
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