In a nutshell This study aimed to investigate the long-term outcomes for patients with stage I-II classic Hodgkin lymphoma and unfavorable risk who were treated with Stanford V combined modality therapy. This study concluded that the long-term outcomes for these patients were favorable and comparable to other standard...
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In a nutshell The study evaluated if brentuximab-vedotin (BV; Adcetris) consolidation therapy can reduce the use of radiation therapy (RT) in patients with limited-stage (LS) Hodgkin lymphoma (HL). The authors found that BV consolidation achieved good outcomes in such patients when given after ABVD therapy. Some background HL is a cancer of the...
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In a nutshell This article outlined the current guidelines for treatment for patients with classical Hodgkin lymphoma (cHL). Some background Treatments for patients with cHL have advanced in the last number of years and most patients can be cured. Treatment options include chemotherapy (CT), radiotherapy (RT), and biological...
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In a nutshell This study examined if ABVD chemotherapy impacted fertility in female patients with Hodgkin lymphoma (HL). The authors found that ABVD reduced the levels of one of the fertility hormones and the type of fertility treatment patients opted for was not affected by ABVD. Some background Many patients with HL are young and fertility...
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In a nutshell This study examined how COVID-19 infection affects patients with cancer undergoing chemotherapy and the role of other factors in COVID-19 complications. The results showed that patients with advanced age and other medical conditions had a higher risk of COVID-19 complications but chemotherapy treatment did not need to be stopped. Some...
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In a nutshell This study aimed to compare outcomes of allogeneic hematopoietic stem cell transplant (alloHSCT) using cryopreserved (frozen) and fresh grafts in patients with blood cancers who received post-transplant cyclophosphamide (Cytoxan). This study concluded that cryopreservation (CP) does...
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In a nutshell This study examined if radiotherapy (RT) would benefit patients with advanced Hodgkin lymphoma (HL) with small tumors following chemotherapy. The authors found that RT may increase patients’ survival without worsening of HL, although this may also increase side effects. Some background Treatment options for patients with...
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In a nutshell This study compared the effectiveness and safety of ABVD and BEACOPP chemotherapy for patients with advanced Hodgkin lymphoma (HL). The authors found that while BEACOPP was more effective in the short term, ABVD was as effective in the long term and safer for patients. Some background Chemotherapy is the standard initial treatment...
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In a nutshell This article reviewed the current treatment options for patients with Hodgkin lymphoma (HL). Some background Treatment options for patients with HL depend on the type of HL, stage of the disease, and the presence of risk factors. The stage of HL represents how widespread or severe the cancer is. Risk factors indicate that there...
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In a nutshell This study examined older patients with Hodgkin lymphoma (HL) to understand how other serious health conditions affect their diagnosis and treatment. The authors found that patients with more serious illnesses were more likely to be diagnosed with advanced HL and had limited treatment options. Some background Treatment options for...
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In a nutshell This study compared ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) and brentuximab vedotin (Adcedris; A) + AVD (doxorubicin, vinblastine, and dacarbazine) chemotherapy combinations to understand which is more effective long term for patients with advanced classical Hodgkin lymphoma (HL). The authors concluded...
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In a nutshell This study compared ways to interpret PET scans to see which best predicted treatment results for older patients with Hodgkin lymphoma (HL). The authors identified several methods of PET scan analysis that were able to predict how effective treatment was for these patients. Some background PET scans are often used to diagnose...
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