In a nutshell This study determined whether targeted radiotherapy reduced the risk of secondary breast cancer in women with Hodgkin lymphoma compared to radiotherapy delivered to a larger area. The authors concluded that while larger field radiation was associated with an increased risk of breast cancer, targeted approaches did not...
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The effects of brentuximab vedotin on quality of life
In a nutshell This trial examined the quality-of-life (QOL) impact of an antibody therapy among patients who had already undergone standard treatment for relapsed- or refractory disease. The authors concluded that the treatment modestly decreased QOL during certain time periods only. Some background Hodgkin Lymphoma is generally highly...
Read MoreReducing time between salvage chemotherapy cycles in relapsed or refractory Hodgkin lymphoma
In a nutshell This study determined whether a faster course of salvage chemotherapy reduced tumor volume in patients with relapsed or refractory Hodgkin lymphoma. The authors concluded that shorter intervals between SC cycles was safe and effective. Some background Hodgkin lymphoma is considered to be a highly curable form of...
Read MoreGuest Post: Cancer On Facebook–A Patient’s Perspective
Dawn Goo is a waitress, former comedian, breast cancer survivor and is now under treatment for Non Hodgkins Lymphoma. She lives in El Paso, Texas. This is a post from her Facebook page which is gathering momentum in social media among people who have experienced cancer, especially those who are dealing with Stage 4 disease. DAMN IT DAWN! WE ONLY WANT...
Read MoreAre end-of-treatment PET scans necessary?
In a nutshell This study investigated whether end-of-treatment PET scans could be left out if the mid-treatment scans were negative (no cancer activity). The authors concluded that the end-of-treatment scans were essential, even in patients with negative interim results. Some background Positron emission tomograpy (PET) scans are used to...
Read MoreABVD versus Stanford V chemotherapy for early-stage, bulky Hodgkin lymphoma
In a nutshell This trial compared the outcomes of ABVD and Stanford-V chemotherapy in patients with stage I or stage II bulky Hodgkin lymphoma. The authors concluded that both treatments were equally effective. Some background Hodgkin Lymphoma is a cancer of the lymph system. Patients with bulky disease have tumors larger than 10 cm....
Read MorePET-scans and treatment options in early-stage Hodgkin lymphoma
In a nutshell This trial examined the need for radiotherapy among early-stage Hodgkin lymphoma patients who responded well to chemotherapy. The authors concluded that in these patients, progression-free survival rates were high overall, but were slightly higher with additional radiation. Some background Hodgkin lymphoma is a cancer...
Read MoreWhat pediatric Hodgkin lymphoma patients benefit from radiation after chemotherapy?
In a nutshell This trial examined which children with Hodgkin lymphoma benefit from radiation therapy after chemotherapy. The authors concluded that patients with a combination of bulky disease (tumors larger than 6 cm) and anemia (low levels of red blood cells) benefited most. Some background Hodgkin lymphoma is a cancer of the lymph...
Read MoreRadiation therapy after stem-cell transplantation is safe and effective for relapsed- or refractory Hodgkin lymphoma
In a nutshell This study assessed whether patients with relapsed- or refractory Hodgkin Lymphoma should be treated with radiation therapy. The authors concluded that radiation therapy was safe and prevented the return of the disease in certain patients. Some background Hodgkin lymphoma is a cancer of the lymph system. It is a...
Read MoreBleomycin lung toxicity is not associated with the risk of radiation lung injury in Hodgkin lymphoma
In a nutshell This study investigated whether or not there was an increased risk of radiation pneumonitis (RP, radiation-induced lung injury) in Hodgkin lymphoma patients treated with the chemotherapy bleomycin. The authors concluded that there was no association between bleomycin lung effects and RP. Some background...
Read MoreBendamustine is effective in Hodgkin lymphoma that has relapsed or did not respond to treatment
In a nutshell This trial examined the effectiveness of bendamustine in patients with Hodgkin lymphoma that did not respond to treatment or returned after a period without disease. The authors found that this treatment was effective in this population. Some background About 30% of Hodgkin lymphoma patients will either not respond to treatment...
Read MoreRadiation techniques in early-stage Hodgkin lymphoma
In a nutshell The current study examined the use of involved node radiation therapy with different delivery techniques in patients with early-stage Hodgkin lymphoma. The study suggests that radiation to a smaller area is safe and effective in these patients. Some background The main treatment options for Hodgkin lymphoma are chemotherapy combined...
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