In a nutshell This review aimed to determine the accuracy of F-fluoro-2deoxy-D-glucose positron emission tomography (FDG-PET) scans at predicting the success of autologous (using the patient’s own stem cells) stem cell transplant (SCT). This study concluded that an FDG-PET scan before SCT may be of value in predicting the outcome of the SCT...
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In a nutshell The authors looked at the relationship between heart failure and different treatments for Hodgkin Lymphoma. This study concluded that the risk of heart failure increased with increasing radiation doses and the use of chemotherapy containing anthracyclines (such as doxorubicin). Some background Hodgkin lymphoma (HL) has high 10-year...
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In a nutshell This study examined factors important in treatment selection for early-stage classical Hodgkin lymphoma. Researchers reported that cancer markers, age, and tumor location as well as gender, ethnicity, distance to facility, and type of insurance affected treatment selection. Some background Classical Hodgkin lymphoma is the most...
Read MoreIn a nutshell This study reviewed evidence on treatment options for classical Hodgkin lymphoma during pregnancy. Authors concluded that standard chemotherapy during the second and third trimester is generally considered safe and effective. However, more high-quality evidence is needed. Some background Hodgkin lymphoma (HL) is a cancer of the lymph...
Read MoreIn a nutshell This review provided guidelines relating to the treatment of nodular lymphocytic-predominant Hodgkin lymphoma (NLPHL). The authors concluded that appropriate treatment varied by age, disease-stage and the presence of relapse. Some background NLPHL is the rarer form of HL. It is characterized by the presence of atypical white...
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In a nutshell This study determined whether certain risk factors predicted outcomes in primary refractory Hodgkin lymphoma. The authors concluded that risk factors such as stage IV disease and cancer activity seen on imaging predicted worse overall outcomes. Some background Refractory disease Hodgkin lymphoma patients are those who are...
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In a nutshell This study compared the survival outcomes of two different age groups of relapsed and refractory Hodgkin lymphoma patients. The authors concluded that co-morbidities, not age, reduced survival rates after stem-cell surgery. Some background Hodgkin lymphoma (HL) is a type of cancer of the lymph system. It is generally highly...
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In a nutshell This study examined the healthcare usage of Hodgkin Lymphoma survivors. The authors concluded that survivors had increased healthcare usage up to 10 years after treatment. Some background Survivors of Hodgkin lymphoma (HL) sometimes experience late treatment effects. These include secondary lung cancer, secondary...
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In a nutshell This study evaluated the effectiveness of brentuximab-vedotin therapy in relapsed- and refractory Hodgkin lymphoma patients. The authors concluded that the treatment was safe and effective. Some background Some Hodgkin lymphoma patients are either unresponsive to treatment (refractory disease), or relapse soon...
Read MoreIn a nutshell This study determined the impact of cancer-related fatigue on Hodgkin-Lymphoma patients and survivors. The authors concluded that fatigue particularly affected social integration. Some background Hodgkin-Lymphoma (HL) patients and survivors can experience persistent cancer-related fatigue. Reports of fatigue occur 2.5 to 3...
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In a nutshell This study determined whether risk-adapted, salvage-chemotherapy response improved survival in patients with relapsed or refractory disease. The authors concluded that treating patients based on their number of risk factors improved outcomes. Some background Some Hodgkin lymphoma patients either do not respond to treatment...
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In a nutshell This study summarized key guidelines for the diagnosis, treatment, and follow-up of classical Hodgkin lymphoma. Some background Hodgkin lymphoma (HL) is a cancer of the lymph system. Classical HL is the most common form and considered very treatable. It mostly occurs in young adults aged 20 to 34 years, but is also seen in adults...
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