In a nutshell This study is investigating the effectiveness of brentuximab vedotin (Adcetris) and nivolumab (Opdivo) in early-stage Hodgkin lymphoma (HL). The main outcome that will be measured will be survival without cancer worsening after 18 months. The details There are many different treatments for HL. Each treatment or combination of...
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Does PET/CT scanning affect treatment and survival of patients with lymphoma?
In a nutshell This study examined the effect of PET/CT scanning on the treatment and survival of patients with lymphoma. Researchers found that PET/CT improved the management plan and survival of these patients. Some background PET/CT are types of scans that detect changes in cells and tissues inside the body. They can be used to check the sites of...
Read MoreEvaluating the impact of early PET/CT scanning on survival in patients with lymphoma after stem cell transplant
In a nutshell This study evaluated the impact of early FDG PET/CT scanning on the survival of patients with lymphoma after allogeneic stem cell transplantation (alloSCT). This study concluded that having positive scan results at 3 months after alloSCT may highly predict relapse and poor survival in these patients. Some background An alloSCT is a...
Read MoreEvaluating the impact of early PET/CT scanning on survival in patients with lymphoma after stem cell transplant
In a nutshell This study evaluated the impact of early FDG PET/CT scanning on the survival of patients with lymphoma after allogeneic stem cell transplantation (alloSCT). This study concluded that having positive scan results at 3 months after alloSCT may highly predict relapse and poor survival in these patients. Some background An alloSCT is a...
Read MoreEvaluating a new targeted therapy with or without itacitinib for relapsed or refractory lymphoma
In a nutshell This study evaluated the safety and effectiveness of a new targeted therapy (INCB040093) with or without itacitinib in patients with relapsed or refractory (does not respond to treatment) lymphoma. This study concluded that this new agent was well-tolerated and showed promising effectiveness in these patients. Some background...
Read MoreTiredness in children and teenagers with leukemia/lymphoma and stem cell transplants.
In a nutshell This study aimed to identify risk factors of tiredness in children treated for leukemia and lymphoma or who received a stem cell transplant. Researchers found that older age and active treatment were risk factors for developing severe tiredness in these patients. Some background Cancer treatment leads to severe tiredness (fatigue) over...
Read MoreEvaluating the impact of autoimmune conditions on the outcomes of patients with lymphoma
In a nutshell This study evaluated the impact of autoimmune conditions on the outcomes of patients with lymphoma. This study concluded that these conditions may negatively impact survival outcomes for these patients. Some background Autoimmune conditions are a group of diseases where the immune system attacks the body’s healthy tissues. One...
Read MoreDo ACE inhibitors help with anthracycline-induced cardiotoxicity in leukemia and lymphoma?
In a nutshell This study aimed to investigate if enalapril influences anthracycline-induced cardiotoxicity in children with leukemia and lymphoma. This study concluded that enalapril has a role in reducing anthracycline-induced cardiotoxicity in these patients. Some background Anthracyclines are a class of chemotherapy drugs that can be used for...
Read MoreEvaluating brentuximab vedotin plus gemcitabine in children and young adults with relapsed or refractory Hodgkin’s lymphoma
In a nutshell This study evaluated the safety and effectiveness of brentuximab vedotin (Adcetris) plus gemcitabine (Gemzar) in children and young adults with relapsed or refractory (does not respond to treatment) Hodgkin’s lymphoma (HL). This study concluded that this combination is safe and shows promising effectiveness in these...
Read MoreIs blood cell transplant effective in HIV-associated lymphoma?
In a nutshell This study investigated the effects of blood cell transfer in patients with human immunodeficiency virus (HIV) who had developed lymphomas. At 4 years, it was found that 70% of patients survived following blood cell transfer. Some background Lymphomas are forms of cancer which affect the blood cells. Two common types of lymphoma are...
Read MoreSearching for patients with relapsed or refractory Hodgkin’s lymphoma to try pembrolizumab plus GVD
In a nutshell This trial is evaluating the effects of second-line pembrolizumab (Keytruda) plus GVD (gemcitabine, vinorelbine, doxorubicin) for relapsed (recurrent cancer) or refractory (does not respond to treatment) Hodgkin’s lymphoma (HL). The main outcome to be measured is the number of patients who achieve a complete response...
Read MoreEvaluating resminostat for patients with relapsed or refractory Hodgkin’s lymphoma
In a nutshell This study evaluated the safety and effectiveness of resminostat in heavily pre-treated patients with relapsed or refractory (does not respond to treatment) Hodgkin’s lymphoma (HL). This study concluded that resminostat was effective and well-tolerated in these patients. Some background Histone deacetylase inhibitors (HDIs)...
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