In a nutshell This study investigated female fertility preservation (FFP) in cancer patients. They found that FFP should be discussed with all women of reproductive age undergoing cancer treatment. Some background Cancer can have many negative effects on patient health. Infertility is a particular concern for younger female patients. Pregnancy rates...
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In a nutshell This study is evaluating how well a new chemoimmunotherapy regimen works in treating patients with classical Hodgkin’s lymphoma (cHL) that has come back or stopped responding to treatment. The main outcome to be measured will be the number of patients who have a complete disappearance of all signs of cancer after treatment. This study...
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In a nutshell This article reviewed current treatment options for elderly patients with Hodgkin lymphoma (HL). Some background There are two main types of Hodgkin’s lymphoma. These include classical HL (cHL) and nodular lymphocyte-predominant HL (NLPHL). NLPHL is the rarer of these two types. Chemotherapy and radiation are the foundations...
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In a nutshell This article reviewed different options for first-line treatment for Hodgkin lymphoma (HL). Some background Treatment for patients with HL has become more individualized. Treatment strategies have been adapted to disease risk, and how well patients respond to initial treatment. The goal of these approaches is to reduce side effects...
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In a nutshell This study looked at the safety and effectiveness of pembrolizumab (Keytruda) in the treatment of patients with relapsed or unresponsive Hodgkin lymphoma after stem cell transplant. Researchers found that pembrolizumab was a safe and effective treatment when used in this way. Some background Hodgkin lymphoma is a cancer of the immune...
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In a nutshell This study investigated whether interleukin-2 receptor levels in the blood influenced the outcomes of patients with classical Hodgkin’s lymphoma (cHL). This study concluded that this can be a useful tool for predicting prognosis for these patients. Some background Chemotherapy remains the standard first-line treatment for HL. One...
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In a nutshell This article reviewed current treatment options for patients with Hodgkin lymphoma (HL) that has come back (relapsed) or stopped responding to treatment (refractory). Some background Chemotherapy remains the standard first-line treatment for HL. One of the most commonly used regimens is ABVD (doxorubicin, bleomycin, vinblastine,...
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In a nutshell This study evaluated the effectiveness and safety of a modified chemotherapy regimen for patients with early-stage Hodgkin lymphoma (HL). This study concluded that this regimen was effective but associated with more side effects. Some background The most commonly used frontline chemotherapy regimen for HL is ABVD (doxorubicin,...
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In a nutshell This study evaluated the outcomes of pediatric patients with high-risk Hodgkin lymphoma (HL) after response-adapted treatment. This study concluded that PET scanning during treatment can help adapt further treatments and improve outcomes for these patients. Some background For most pediatric patients with HL, outcomes after...
Read MoreIn a nutshell This phase 1 study is evaluating the safety and effectiveness of a new T-cell therapy combined with nivolumab (Opdivo) for patients with lymphoma that has come back or stopped responding to treatment. The main outcome to be measured will be the number of patients who have side effects. This study is recruiting in Washington, D.C. and Salt...
Read MoreIn a nutshell This study will investigate the effects of high-pressure oxygen on the transplant of umbilical cord blood stem cells in patients with blood cancers. The main outcome that will be measured is the time it takes for white blood cells to recover after treatment. This trial is recruiting in New York, US. The details Stem cell transplant is...
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In a nutshell This study evaluated the outcomes of patients with classical Hodgkin lymphoma (cHL) after reduced-intensity chemotherapy and haploidentical stem cell transplantation (haploSCT). This study concluded that this treatment approach is as effective as allogeneic SCT (alloSCT), but with fewer long-term complications. Some background...
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