In a nutshell This study analyzed the effectiveness of pioglitazone (Actos) in patients with prediabetes or type 2 diabetes (T2D) and nonalcoholic fatty liver disease (NAFLD). The authors concluded that pioglitazone can significantly improve liver function in these patients. Some background NAFLD is the accumulation of fat cells in the...
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In a nutshell This review looked at whether exercise can improve heart rate variability (HRV) for patients with type 2 diabetes (T2D). It found that exercise improved HRV, which indicates better nerve health of the heart. Some background Over time, high blood glucose (sugar) from diabetes can cause nerve damage or neuropathy. People with diabetes...
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In a nutshell This study looked at how the Diabeloop system managed exercise for patients with type 1 diabetes (T1D). It found that people using this system did not have more hypoglycemia (dangerously low blood sugar) on days with exercise. Some background Physical exercise is a cornerstone of good health. Its many benefits include improved heart...
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In a nutshell In this study, the authors evaluated the effectiveness of adding dapagliflozin (Farxiga) to insulin therapy in patients with uncontrolled type 2 diabetes (T2D). The study showed that compared to increasing insulin doses, dapagliflozin improved glucose control while reducing weight and hypoglycemia (dangerously low blood...
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In a nutshell This study evaluated the addition of linagliptin (Trajenta) to metformin (Glucophage) and lifestyle changes in patients with persistent prediabetes. The authors concluded that adding linagliptin after 12 months of metformin treatment and lifestyle changes improved glucose levels and pancreatic β-cell function in these...
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In a nutshell This study compared the effectiveness and tolerance of metformin (Glucophage) extended-release (MXR) and conventional metformin immediate-release (MIR) in adults with type 2 diabetes (T2D). The authors concluded that MIR had better glucose control while MXR but reduced gastrointestinal (GI) side effects. Some background...
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In a nutshell This review looked at whether medications similar to the GLP-1 hormone can improve liver health for people with type 2 diabetes (T2D) and fatty liver disease. It found that these medications can improve liver health and reduce fat in the liver. Some background As many as 60% of people with T2D also develop non-alcoholic fatty liver...
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In a nutshell This study compared metformin (Glucophage) to insulin for women with diabetes during pregnancy. It found that metformin was equally good at preventing high blood sugar, but led to less hypoglycemia (dangerously low blood glucose), less weight gain, and fewer cesarean sections. Some background Gestational diabetes (GD) is one of the most...
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In a nutshell This study looked at whether myoinositol and α-lactalbumin can benefit women with diabetes during pregnancy. It found that these supplements may reduce insulin resistance and pre-term birth in these women. Some background Gestational diabetes (GD) occurs when a pregnant woman’s body becomes resistant to the hormone...
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In a nutshell This trial looked at how zinc and curcumin supplements affected people with prediabetes. It found that these supplements improved blood sugar and sensitivity to insulin. Some background Prediabetes is a condition in which the amount of glucose (sugar) in the blood is starting to become higher than normal. Prediabetes increases the risk...
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In a nutshell This study looked at how weekly semaglutide (Ozempic) affected patients with type 2 diabetes (T2D) in a real-world setting. It found that semaglutide improved blood sugar control compared to the treatments patients were already taking. Some background For patients with T2D, the body does not respond well to the hormone insulin, which...
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In a nutshell This study compared the effectiveness and safety of biphasic insulin aspart 30 (BIAsp 30; NovoMix 30) alone or with metformin (Glucophage), in patients with inadequately controlled type 2 diabetes (T2D). The authors concluded that combined therapy may be preferred in patients with high cardiovascular risk and/or a body...
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