In a nutshell This study compared the effect of administering 1.5 mg, 3 mg, and 4.5 mg of dulaglutide (Trulicity) on overall bodyweight reduction in patients with type 2 diabetes (T2D). The authors concluded that higher doses of dulaglutide caused more weight loss in these patients. Some background Abnormal or excessive levels of fat in the...
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In a nutshell This study looked at continuous subcutaneous insulin infusions (CSII) for the treatment of diabetic retinopathy (DR; eye disease). It found that compared to multiple daily injections of insulin (MDI), CSII resulted in a less worsening of DR. Some background Diabetic eye disease, also called diabetic retinopathy (DR), is a...
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In a nutshell This study looked at the risk of urogenital infections in patients with diabetes taking sodium-glucose co-transporter 2 (SGLT2) inhibitors. It found that SGLT2 inhibitors increase the risk of urogenital infections in women over 50 years of age, especially in the first month of treatment. Some background SGLT 2 inhibitors such...
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In a nutshell This study compared mecobalamin (vitamin B12) injections with mecobalamin tablets for the treatment of diabetic peripheral neuropathy (DPN; nerve damage). It showed that after 8 weeks of treatment, patients treated with mecobalamin injections showed signs of nerves being repaired, while no effects were seen in those taking...
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In a nutshell This study looked at tirzepatide, a new treatment for type 2 diabetes, compared to semaglutide (Ozempic). It found that, depending on the dose, tirzepatide was similarly or more effective at controlling blood glucose than semaglutide. Some background Tirzepatide is a new type of medication designed to treat type 2...
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In a nutshell This review looked at whether antioxidant supplements can reduce inflammation for women with diabetes during pregnancy (gestational diabetes; GDM). It found that supplements including omega-3, vitamin D, and magnesium reduced oxidation in the body for these women. Some background During late pregnancy, the body becomes less sensitive to...
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In a nutshell This study looked at the effects of dulaglutide (Trulicity) on erectile function in men with type 2 diabetes (T2D). It found that men with T2D taking dulaglutide were less likely to develop erectile dysfunction (ED) than those taking a placebo. Some background ED is a common complication of T2D. It involves an...
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In a nutshell This study evaluated whether liraglutide (Victoza) improves diabetic control in patients with difficult to control type 2 diabetes (T2D) and if there were certain factors that influence the effects of liraglutide. It found that patients responded equally well to liraglutide regardless of body mass index (BMI; a measurement of...
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In a nutshell This review looked at whether bariatric (weight-loss) surgery (BS) improves life expectancy for adults with or without type 2 diabetes (T2D). It found that BS improved life expectancy for people with diabetes by 9.3 years. Some background Diabetes, or high blood glucose (sugar), is a chronic condition that affects overall health. Long...
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In a nutshell This study looked at the use of piperazine ferulate (PF) in diabetic patients. It found that adding PF to angiotensin receptor blocker (ARB) treatment helped to protect kidney function in patients with diabetes. Some background Diabetic kidney disease is a complication of diabetes. It can result in patients losing...
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In a nutshell This study looked at the safety and effectiveness of tirzepatide (LY-3298176) in patients with type 2 diabetes (T2D) inadequately controlled by diet and exercise alone. It found that compared to placebo, tirzepatide improved diabetes control and weight in these patients. Some background In T2D, there is a resistance of the...
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In a nutshell This review looked at whether sodium-glucose cotransporter 2 (SGLT2) inhibitors can improve non-alcoholic fatty liver disease (NAFLD) for people with type 2 diabetes (T2D). It found that these medications can improve liver function in these patients. Some background NAFLD is a condition in which fat builds up in the liver. This makes the...
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