In a nutshell This study compared the effectiveness and safety of a combination of insulin glargine (Lantus) and lixisenatide (Lyxumia), called iGlarLixi, to either drug on its own, in people with type 2 diabetes (T2D). It was determined that iGlarLixi was more effective in reducing HbA1c, and did not increase the risk of side effects. Some background...
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Can semaglutide control blood glucose without side effects?
In a nutshell This study investigated the safety and effectiveness of semaglutide (Ozempic) in people with type 2 diabetes (T2D). It was determined that semaglutide lowers HbA1c (measures average blood glucose over the last 3 months) without significantly increasing weight gain, hypoglycemia, or gastrointestinal (GI) side effects. Some background...
Read MoreWhat is the best target for blood pressure in people with type 2 diabetes?
In a nutshell This study investigated the ideal blood pressure target for people with type 2 diabetes (T2D). It was determined that a systolic blood pressure (SBP, pressure when the heart contracts) of 130-139 mmHg reduced complications of high blood pressure, but there was limited evidence that lowering of SBP below 130 mmHg had benefits, and that...
Read MoreInsulin pump failure in children with type 1 diabetes
In a nutshell This study investigated failure of insulin pumps in children and adolescents with type 1 diabetes (T1D). It was determined that insulin pumps failed at a rate of 4.5% per year in these patients. Some background A traditional insulin pump is a small device that continuously delivers insulin, without the need for multiple daily injections....
Read MoreEffects of diet on the risk of retinopathy
In a nutshell This study investigated the role of diet in diabetic retinopathy (DR). It was determined that fiber, oily fish, a Mediterranean diet, and reduced caloric intake were associated with a lower risk of DR. Some background DR is a common complication of type 1 diabetes (T1D) and type 2 diabetes (T2D). In DR blood vessels in the retina (part...
Read MoreVegetarian Diet Great for Type 2 Diabetes
Critical benefits may be had from eating a vegetarian diet for people living with type 2 diabetes, a recent meta-analysis of randomized control trials* indicates. Published in Clinical Nutrition, the meta-analysis of nine studies involved over 600 participants taking insulin, oral glucose lowering drugs, lipid-lowering medications or medications to...
Read MoreCan self-monitoring blood glucose improve glycemic control?
In a nutshell This study investigated the effect of self-monitoring of blood glucose on HbA1c (average blood glucose over last 3 months) in people with type 2 diabetes (T2D). It was determined that self-monitoring reduces HbA1c in the short-term, but not the long-term. Some background Treatment for T2D includes lifestyle changes (like diet and...
Read MoreAre broken bones more common in young and middle-aged adults with type 1 diabetes?
In a nutshell This study investigated the risk of fractures (broken bones) in young and middle-aged adults with type 1 diabetes (T1D). It was determined that T1D was associated with a higher risk of fracture in young and middle-aged adults compared to those without T1D. Some background In people with T1D the skeleton is more likely to become...
Read MoreAre people with diabetes more likely to have a respiratory disease?
In a nutshell This study investigated the association of diabetes with respiratory diseases (RDs, breathing problems). It was determined that people with diabetes, especially type 1 diabetes (T1D), were more likely to have an RD. Some background Both T1D and type 2 diabetes (T2D) are associated with changes in the lungs that might make a person more...
Read MoreDo different meals affect glucose levels in people using an artificial pancreas?
In a nutshell This study examined the effects of adding protein and/or fat to a meal with a standard amount of carbohydrates, in adults with type 1 diabetes (T1D) using an artificial pancreas (AP). It was determined adding protein and/or fat did not affect glucose levels over time, but did influence the timing of spikes in glucose levels, and...
Read MoreSafety of non-insulin anti-diabetes drugs in early pregnancy
In a nutshell This study compared the safety of non-insulin anti-diabetes drugs (NIADD) to insulin in early pregnancy in women with diabetes diagnosed before pregnancy. It was determined that NIADD did not increase the risk of miscarriages, stillbirths, or major structural anomalies compared to insulin. Some background Women with diabetes have a...
Read MoreAre new combinations of insulin safe and more effective?
In a nutshell This study investigated the safety and effectiveness of a combination of two different types of insulin (IDegAsp) in people with type 2 diabetes (T2D). It was determined that IDegAsp was safe and effective at controlling blood glucose levels in a variety of patients. Some background People with T2D can control their symptoms, at first,...
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