In a nutshell This trial is examining the safety and effectiveness of the new drug MYL-1601D in comparison to Novolog (fast-acting insulin) in the treatment of type 1 diabetes (T1D). The main outcomes to be measured are the antibody response (response of the immune system to the drug) and improvements in blood glucose control. This study is being carried...
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Diacerein reduces liver scarring in diabetic patients with non-alcoholic fatty liver disease
In a nutshell This study aimed to investigate how effective diacerein is in reducing fat deposits and scarring on the liver in patients with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D). The main finding of the study was that diacerein reduced liver scarring in these patients. Some background T2D is commonly associated with...
Read MoreLooking for patients with type 2 diabetes treated with basal insulin to try a new investigational drug
In a nutshell This study is examining the safety and effectiveness of a new insulin plan for people with type 2 diabetes (T2D) that are already being treated with basal insulin. The new insulin being evaluated is a once-a-week administration of insulin instead of daily injections of basal insulin, which should be substantially more convenient for...
Read MoreEffect of myo-inositol on blood glucose in patients with gestational diabetes
In a nutshell The aim of this study was to investigate the effect of myo-inositol on the changes in blood glucose levels in women with gestational diabetes. The main finding was that myo-inositol was effective in reducing changes in blood glucose levels in these patients. Some background Insulin is the hormone that controls blood glucose. It helps...
Read MoreHow safe and effective is ertugliflozin in patients with type 2 diabetes?
In a nutshell The aim of this study was to evaluate how safe and effective ertugliflozin (Steglatro) is in patients with type 2 diabetes (T2D) that is not controlled well with metformin (Glucophage). The study found that ertugliflozin is safe and improved blood glucose control, body weight, and blood pressure in these patients. Some background...
Read MoreShould fiber supplements be considered in diabetes control?
In a nutshell The aim of this study was to see if fiber supplements could have beneficial effects in the treatment of diabetes. The main finding of the study was that fiber supplements improved blood glucose control in type 2 diabetes (T2D). Some background In T2D, the body becomes insulin resistant. Insulin is a hormone that controls blood glucose....
Read MoreMultiple daily injections compared with using an insulin pump in pregnant women with type 1 diabetes
In a nutshell This study compared the effectivess of an insulin pump with multiple daily injections in patients with type 1 diabetes during pregnancy. The study found that women who used MDI had better blood sugar control and lower blood pressure. Some background Women with type 1 diabetes are able to have babies very safely, as long as their blood...
Read MoreHow safe and effective is fast-acting insulin aspart in a continuous insulin infusion in type 1 diabetes?
In a nutshell The aim of this study was to investigate how safe and effective fast-acting insulin aspart (faster aspart) is compared to insulin aspart (NovoRapid, NovoLog) when used in a continuous insulin pump in type 1 diabetes (T1D). The main finding was that faster aspart is a safe and effective option in a continuous insulin pump for these...
Read MoreEvaluating the effectiveness of a new drug for treatment of diabetic kidney disease
In a nutshell The aim of this study is to see how effective the new drug (ASP8232) is in the treatment of diabetic kidney disease. The main finding of the study was that ASP8232 effectively reduced the amount of protein in the urine (a marker of kidney disease) in patients with diabetic kidney disease. Some background Diabetic kidney disease...
Read MoreLooking for patients with painful diabetic nerve disease to test new pain-relief treatment
In a nutshell This trial is examining the effectiveness of new drug Omnitram to relieve pain in painful diabetic nerve disease. The main outcome to be measured will be pain intensity. This study will be carried out in Missouri and Texas, United States. The details Diabetic nerve disease (neuropathy) is a common complication of diabetes. When there are...
Read MoreLooking for patients with type 2 diabetes and non-alcoholic fatty liver disease to test new drug
In a nutshell This study aims to examine the safety and effectiveness of new drug lanifibranor in patients with type 2 diabetes (T2D) and non-alcoholic fatty liver disease (NAFLD). The main outcome to be measured will be a change in intrahepatic triglyceride (amount of fats within the liver). This study is being conducted in the United States. The...
Read MoreLow phosphate and magnesium levels are associated with diabetic nerve disease
In a nutshell The aim of this study was to examine the relationship between levels of blood magnesium and phosphate and diabetic nerve disease. The main finding of the study was that low levels of phosphate and magnesium in the blood were associated with diabetic nerve disease. Some background Patients with diabetes can develop diabetic...
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