In a nutshell This article investigated the safety and effectiveness of sitagliptin (Januvia) in the management of type 2 diabetes (T2D) in elderly patients on insulin. The authors concluded that the addition of sitagliptin is effective and safe in all patients receiving it as add-on therapy to insulin. Some background In type 2...
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The effect of blood sugar awareness on weight retention after gestational diabetes
In a nutshell The aim of this study was to see if women who were aware of their normal blood sugar levels after gestational diabetes (GDM) had more weight retention than those who were unaware of their blood sugar levels. The main finding of the study was that women who knew they had normal blood sugars after GDM had more weight retention than women who...
Read MoreIpragliflozin versus metformin for blood sugar control and fat reduction in type 2 diabetes
In a nutshell The aim of this study was to compare the effectiveness of ipragliflozin compared to metformin in improving blood sugar control and reducing fat on organs in patients with type 2 diabetes (T2D) treated with sitagliptin. The main finding of the study was that ipragliflozin had greater reductions in fat but metformin had better blood sugar...
Read MoreCan high blood pressure lead to nerve disease in type 1 diabetes?
In a nutshell The aim of this study was to investigate if high blood pressure contributes to nerve disease (diabetic neuropathy; DN) in type 1 diabetes (T1D). The main finding of the study was that high blood pressure does contribute to impaired nerve conduction in T1D. Some background Diabetic nerve disease (DN) is a common complication of...
Read MoreWeight management programme led by family doctors for reversing type 2 diabetes
In a nutshell The aim of this study was to assess the remission of type 2 diabetes (T2D) during a family doctor-led weight management programme. The main finding of the study was that after 2 years of the programme more than one-third of patients had reversed their T2D. Some background The number of people with T2D is increasing. One factor is the...
Read MoreNew automatic insulin dosing system for type 2 diabetes
In a nutshell The aim of this study was to determine whether a combination of a new insulin dosing system, the d-Nav device and the support of a healthcare professional (HCP) is better than support by an HCP alone. The main finding of the study was that the d-Nav device and HCP together offer better blood sugar control than just the HCP support...
Read MoreHigh night-time blood sugar level associated with large baby in women with gestational diabetes
In a nutshell The aim of this study was to investigate the role of glucose changes in the development of a large baby in women with gestational diabetes. The main finding of the study was that mothers who had large babies had high blood glucose levels at night. Some background Gestational diabetes mellitus (GDM) is diabetes that occurs during...
Read MoreStem cell containing gel for the treatment of diabetic foot ulcers
In a nutshell The aim of this study was to examine the effects of adipose-derived stem cell (ASC) sheets in the treatment of diabetic foot ulcers (DFU). The main finding of the study was that ASC sheets improved the healing of DFU. Some background DFUs are a common complication of diabetes. DFUs are very difficult to heal and can result in pain,...
Read MoreSGLT2 inhibitors to prevent heart and kidney disease in type 2 diabetes
In a nutshell The aim of this study was to investigate the effect of SGLT2 inhibitors on the prevention of heart and kidney disease in patients with type 2 diabetes (T2D). The main outcome was that SGLT2-inhibitors reduced hospitalization for heart failure and prevented the worsening of kidney disease in T2D. Some background There are many...
Read MoreDapagliflozin in type 1 diabetes
In a nutshell The aim of this study was to assess continuous blood glucose levels in patients with type 1 diabetes (T1D) taking dapagliflozin as an add-on to insulin treatment. The main finding of the study was that patients treated with dapagliflozin had improved average blood glucose levels and less variation in blood glucose levels. Some background...
Read MoreIron deficiency and depression in type 1 diabetes
In a nutshell The aim of this study was to investigate the relationship between iron deficiency and depression in patients with type 1 diabetes (T1D). The main finding of the study was that there was an association between iron deficiency and depression and reduced quality of life in T1D. Some background Iron deficiency (ID) is the most common form of...
Read MoreEvaluating the safety and effectiveness of pioglitazone in type 2 diabetes
In a nutshell The aim of this study was to investigate the safety and effectiveness of pioglitazone in the treatment of type 2 diabetes (T2D). The main finding of the study was that pioglitazone was an effective treatment of T2D. Some background Insulin is the hormone that controls blood sugar. In T2D, patients have insulin resistance. This means that...
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